Dr. Tommy Wood

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1,133 appearances 1 recordings 1 series first heard Jul 2026 last heard 20 Jul

Dr. Tommy Wood’s voice in public audio — every appearance, attributed to the second.

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Huberman Lab · Accelerate Learning & Increase Cognitive Capacity | Dr. Tommy Wood · 20 Jul 2026 podcast

So sleep was one.

Then the other one was nutrient status.

So they didn't talk about omega-3s, B vitamins, which we do actually have some quite high quality interventional and observational kind of epidemiological data for.

So there was kind of some discussion as to whether those things should have been included.

Other analyses that looked at those suggested that they potentially contribute a significant amount of the population attributable risk of dementia.

So all that to say that...

their 45% estimate could be quite conservative if we consider some of the other things.

There are some other studies that suggest that maybe as many as, or as much as 70% of dementias may be preventable, but then you have to start including things related to socioeconomic status and deprivation and other societal factors that we know have a massive impact as well.

So that's less modifiable like on the individual level, right?

It really would require changes at the societal level, which is kind of harder to do.

This comes off the back of

three or four very large natural experiments that have been done in various countries.

And really how you interpret these data is going to depend a little bit on your kind of risk tolerance and like how, what you think should be done in terms of the level of evidence required to intervene.

So I'll describe the studies in a second, but some people are definitely saying, you know, if you want to say that,

the shingles vaccine decreases dementia risk, you have to have a clinical trial that's adequately powered to show that.

And there is a trial like that being planned currently.

So the studies that have happened so far, there was one in the UK, in Wales, one in Australia, and one in Canada.

And in each of those countries, what happened was that on a single date,

a huge tranche of people became eligible to get the shingles vaccine, whereas if they were born one day earlier, they weren't eligible.

So you get what we call a natural experiment, where from one day to the next, those people shouldn't be that different otherwise.

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