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Eric Topol

๐Ÿ‘ค Speaker
See mentions of this person in podcasts
3037 total appearances

Appearances Over Time

Podcast Appearances

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

If you can predict, if you can query, if you can generate like that, it's reminiscent of the famous Go game of Lee Soto, the world champion player.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

and how the machine came up with a move many, many years ago that no human would have anticipated.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

I think that's what you're getting at and the ability for inference and reason now to add to this.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

Charlotte, one of the things, of course, is about, well, there's two terms in here that are unfamiliar to many of the listeners or viewers of this podcast.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

Universal representations and virtual instruments that you make a pretty significant part of how you are going about this virtual cell model.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

So could you describe that and also the embeddings as part of the UR, the universal representation?

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

Because I think embeddings or these meaningful relationships are key to what Steve was just talking about.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

Yeah, that's what I really liked, is that you basically described the architecture of how you're going to do this by putting these URs into the VIs, having a decoder and a manipulator, and you basically got the idea.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

If you can bring all these different integrations about, which, of course, is pending.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

Now, there are obviously many naysayers here that this is impossible.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

One of them is this guy, Philip Ball.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

I don't know if you read the language, How Life Works.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

Now, he's a science journalist, and he's a prolific writer.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

He says, comparing life to a machine, a robot, a computer, sells it short.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

Life is a cascade of processes, each with a distinct integrity and autonomy, the logic of which has no parallel outside the living world.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

Is he right?

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

There's no way to bottle this.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

It's silly.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

It's too complex.

Ground Truths
Steve Quake and Charlotte Bunne: The Holy Grail of Biology

Well, I mean, to capture people's imagination here, if you're successful and you marshal a global effort, I don't know who's going to pay for it because it's a lot of work coming here going forward.