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Eric Topol

๐Ÿ‘ค Speaker
See mentions of this person in podcasts
3399 total appearances

Appearances Over Time

Podcast Appearances

Ground Truths
Vagus Nerve Stimulation and the Immune System

you know, I might take the implant, right?

Ground Truths
Vagus Nerve Stimulation and the Immune System

So the problem is, you know, we don't have enough interest in this bioelectronic treatment.

Ground Truths
Vagus Nerve Stimulation and the Immune System

And it's partly because the device industry, you know, overall has a tougher mission.

Ground Truths
Vagus Nerve Stimulation and the Immune System

And you, in a way, have proven that, that, look, you had this hypothesis nailed 20, 30 years ago, and it's only taken until 2025 to finally have an FDA indication and a

Ground Truths
Vagus Nerve Stimulation and the Immune System

a first tier, first rate randomized sham control trial.

Ground Truths
Vagus Nerve Stimulation and the Immune System

So I thought I'd just get you to comment on what's it like to try to advance a hypothesis in the world of devices, because it just seems to be a much bigger obstacle.

Ground Truths
Vagus Nerve Stimulation and the Immune System

Yeah, up until the GLP-1, Ozempic, Humira and the TNF blockers were the biggest drugs in the world for sales.

Ground Truths
Vagus Nerve Stimulation and the Immune System

It shows you how big a deal autoimmune diseases are, the burden in our population.

Ground Truths
Vagus Nerve Stimulation and the Immune System

So anyway, I just want to say, you know, the book is phenomenal, but

Ground Truths
Vagus Nerve Stimulation and the Immune System

What's even more impressive, Kevin, is that you persevered and you tested the hypotheses and you led to breaking out of a new field.

Ground Truths
Vagus Nerve Stimulation and the Immune System

And I just think it's in the early days.

Ground Truths
Vagus Nerve Stimulation and the Immune System

I think there's gonna be a lot more autoimmune diseases

Ground Truths
Vagus Nerve Stimulation and the Immune System

We're already seeing the randomized trial and refractory depression and other areas.

Ground Truths
Vagus Nerve Stimulation and the Immune System

So anyway, congrats.

Ground Truths
Vagus Nerve Stimulation and the Immune System

It's fun to discuss this with you.

Ground Truths
Vagus Nerve Stimulation and the Immune System

I learned a lot, and I know everyone else who joined today did as well.

Ground Truths
Vagus Nerve Stimulation and the Immune System

We'll post this with all the links that we've been talking about, and hopefully we'll have a chance to revisit all this progress in the times ahead.

Ground Truths
Vagus Nerve Stimulation and the Immune System

So thanks very much, Kevin.

Ground Truths
Vagus Nerve Stimulation and the Immune System

Well, thank you.

Ground Truths
Vagus Nerve Stimulation and the Immune System

Keep up the great stuff.