How to be a "Super Ager" (it's not your genes)

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TED Radio Hour 50 min 3 speakers 4 chapters transcribed 4 months ago
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What does it mean to be a super-ager?

Unknown 0:01
On Consider This, NPR's afternoon news podcast, we cover everything from politics to the economy to the world. But every story starts with a question. At NPR, we stand for your right to be curious, to make sense of the biggest story of the day and what it means for you. Follow Consider This wherever you get your podcasts.
Manoush Zomorodi 0:24
This is the TED Radio Hour. Each week, groundbreaking TED Talks. Our job now is to dream big. Delivered at TED conferences. To bring about the future we want to see. Around the world. To understand who we are. From those talks, we bring you speakers and ideas that will surprise you.
Unknown 0:43
You just don't know what you're going to find.
Manoush Zomorodi 0:45
Challenge you.
Unknown 0:46
We truly have to ask ourselves, why is it noteworthy?
Manoush Zomorodi 0:49
And even change you. I literally feel like I'm a different person. Yes. Do you feel that way? Ideas worth spreading. From TED and NPR, I'm Manoush Zomorodi. On the show today, a guide to being a super-ager, living long and well. It's a strange moment for growing old. We live in an era when some seem to be suggesting that aging... I'm that crazy guy trying to not die.
Unknown 1:20
...is optional. He spends $2 million a year attempting to... I think we're entering into a new era where death may no longer be inevitable.
Manoush Zomorodi 1:28
Silicon Valley elite, celebrities, and influencers alike race against the clock to limit signs of aging.
Unknown 1:35
We are essentially hacking human biology.
Manoush Zomorodi 1:37
I've had three facelifts. Everywhere the light touches is Botoxed. People collect more data about their bodies than ever. Having a Fitbit has truly changed my life. And AI is bringing breakthroughs for conditions once thought to be untreatable. AI will help cure diseases.
Unknown 1:55
AI will help cure cancer. Yes, it's already in the process of doing that.
Manoush Zomorodi 1:59
But we're also in an age of insurance inequity and uneven distribution of these medical miracles. Not to mention billion-dollar industries built on selling you alleged cures to growing and looking older. So it's hard to know. What hot trend or medical breakthrough is worth spending your time and money on? And what is, well, bunk?
Eric Topol 2:25
It drives me nuts that things that we have validation with all kinds of great studies and the highest level peer review literature could take years before it gets to implementation.
Manoush Zomorodi 2:37
This is Dr. Eric Topol.
Eric Topol 2:40
I am a cardiologist, author of Super Agers, and I'm a professor and executive vice president at Scripps Research.
Manoush Zomorodi 2:48
Eric is an expert on the best ways to expand not just our lifespan or how long we actually live, but our health span.
Eric Topol 2:58
A lot of this longevity fixation is related to lifespan rather than health span. healthy aging, the average American health span is 64. That's when major diseases creep in and lifespan is 79 on average. So you've got a big gap of about 15 years where your health span is ended and your lifespan continues.
Manoush Zomorodi 3:24
In some ways, Eric's career has been driven by his own personal obsession with the idea that through science and medicine, we can change our aging destiny.
Eric Topol 3:35
I grew up with so many of my family members dying at very young ages, my grandparents and aunts and uncles. I spent a lot of time as a kid going to funerals. And my parents also died at a young age. So I feel like, well, I'm condemned. I'm going to be signing out any time here. So part of it was just understanding our fate, if you will. Part of it is also to shed some light on a field that's had lots of confusion and this equivalence of health span. with lifespan, which is so different that, you know, we need to really compartmentalize these and understand that what drives them are altogether different.
Manoush Zomorodi 4:16
Long before he made a breakthrough discovery in the science of healthy aging, we'll get to that in a minute, he was a curious college student, sure that people's genes held the answer to how long they would live.
Eric Topol 4:29
I always was fascinated by genetics, and I basically set up a major in genetics and wrote a thesis in 1975 called Prospects for Gene Therapy in Man, long before we could sequence genes, of course. That was about 40 years early, I think. But it was more like understanding what makes us tick.

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