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Eric Topol

πŸ‘€ Speaker
See mentions of this person in podcasts
4038 total appearances

Appearances Over Time

Podcast Appearances

TED Radio Hour
How to be a "Super Ager" (it's not your genes)

It's billions and billions of data points for each person.

TED Radio Hour
How to be a "Super Ager" (it's not your genes)

We couldn't think of being able to prevent these diseases without the help of the tools of AI for the analytics.

TED Radio Hour
How to be a "Super Ager" (it's not your genes)

So those are the five domains.

TED Radio Hour
How to be a "Super Ager" (it's not your genes)

They're all going to be part of our ability to predict a person's risk and prevent their age-related disease in the future.

TED Radio Hour
How to be a "Super Ager" (it's not your genes)

Yeah.

TED Radio Hour
How to be a "Super Ager" (it's not your genes)

So when our immune system, which is all of our cells and proteins that fight off not just infections, but keep us from getting cancer and heart disease and

TED Radio Hour
How to be a "Super Ager" (it's not your genes)

neurodegenerative diseases, our immune system starts to lose its integrity as we get older.

TED Radio Hour
How to be a "Super Ager" (it's not your genes)

And it's the process of immunosenescence.

TED Radio Hour
How to be a "Super Ager" (it's not your genes)

And then interdependent with that is inflammation with aging.

TED Radio Hour
How to be a "Super Ager" (it's not your genes)

And so when the immune system is dysregulated, when it's just getting off the rails, it starts to go haywire and makes a lot of these proteins

TED Radio Hour
How to be a "Super Ager" (it's not your genes)

that are basically untoward inflammation, whether it's in the brain or throughout the body, in the walls of arteries.

TED Radio Hour
How to be a "Super Ager" (it's not your genes)

And this is what causes so much trouble.

TED Radio Hour
How to be a "Super Ager" (it's not your genes)

So some inflammation is good and important for healing, but inflammaging is really accelerating and making these age-related diseases take hold.

TED Radio Hour
How to be a "Super Ager" (it's not your genes)

We can accept that we're going to age.

TED Radio Hour
How to be a "Super Ager" (it's not your genes)

Okay, so maybe there'll be reversal of aging someday, but that's a little more far-fetched.

TED Radio Hour
How to be a "Super Ager" (it's not your genes)

But we don't have to accept that we are going to have these age-related big three diseases.

TED Radio Hour
How to be a "Super Ager" (it's not your genes)

heart disease and cancer or neurodegenerative diseases.

TED Radio Hour
How to be a "Super Ager" (it's not your genes)

And so that's where the opportunity lies, that there's so much going on right now that with 20 years advance warning of these conditions in individuals, determining that risk, predicting it, we should be able to get ahead of it and make a big dent in these big three age-related diseases.

TED Radio Hour
How to be a "Super Ager" (it's not your genes)

That's a real big part of it.

TED Radio Hour
How to be a "Super Ager" (it's not your genes)

What we eat is a part of that story.