Eric Topol
π€ SpeakerAppearances Over Time
Podcast Appearances
It's billions and billions of data points for each person.
We couldn't think of being able to prevent these diseases without the help of the tools of AI for the analytics.
So those are the five domains.
They're all going to be part of our ability to predict a person's risk and prevent their age-related disease in the future.
So when our immune system, which is all of our cells and proteins that fight off not just infections, but keep us from getting cancer and heart disease and
neurodegenerative diseases, our immune system starts to lose its integrity as we get older.
And it's the process of immunosenescence.
And then interdependent with that is inflammation with aging.
And so when the immune system is dysregulated, when it's just getting off the rails, it starts to go haywire and makes a lot of these proteins
that are basically untoward inflammation, whether it's in the brain or throughout the body, in the walls of arteries.
And this is what causes so much trouble.
So some inflammation is good and important for healing, but inflammaging is really accelerating and making these age-related diseases take hold.
We can accept that we're going to age.
Okay, so maybe there'll be reversal of aging someday, but that's a little more far-fetched.
But we don't have to accept that we are going to have these age-related big three diseases.
heart disease and cancer or neurodegenerative diseases.
And so that's where the opportunity lies, that there's so much going on right now that with 20 years advance warning of these conditions in individuals, determining that risk, predicting it, we should be able to get ahead of it and make a big dent in these big three age-related diseases.
That's a real big part of it.
What we eat is a part of that story.