Eric Topol

So they basically are intact of the big three age-related diseases.

And that's not common, but that's what we should be achieving at a much higher frequency.

So the lifestyle one, we've learned a lot more about, like, for example, sleep regularity being so important and deep sleep when our brain washes out all of its metabolites that are really pro-inflammatory, toxic to our brain.

That's why deep sleep is so important.

And exercise, not just aerobic, but also strength resistance training and balance training and

We've learned also how social engagement is so critical, being out in nature and, you know, many, many different lifestyle factors, which we didn't realize how important they are.

Now, omics refers to the biologic layers.

We're talking about genes, DNA, our so-called polygenic risk score, because these diseases we've been talking about are not from one gene, but from hundreds of different genes that can interact, but also our proteins.

There's big breakthroughs in proteins.

Now we have these organ clocks where we can tell the pace of each organ in our body from our brain, our immune system, artery, heart, liver, and on and on.

And then there's these biomarkers.

We have this big, big breakthrough for Alzheimer's to be able to predict even 20 or more years in advance, so-called P-tau-217.

So, omics are proteins and genes and the microbiome of our gut and the side chains of our DNA called methylation.

Those are omics.

This is a big area because we're going to be using cell therapy for lots of things like autoimmune disease.

We've seen cures potentially for people with refractory lupus and multiple sclerosis and many autoimmune diseases, which was unfathomable until recent times.

Using cell therapy, not just take cells out of the body, but working with lymphocytes that are in the body.

Vaccines and drugs that basically keep our immune system healthy and are potent anti-inflammatories.

We've seen a remarkable class of drugs, the Ozempic GLP-1 drugs that have that property.

We couldn't pull all these data together in any individual without multimodal AI.