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Eric Topol

๐Ÿ‘ค Speaker
See mentions of this person in podcasts
3037 total appearances

Appearances Over Time

Podcast Appearances

Ground Truths
Priscilla Chan & Jennifer Doudna: New Center for Pediatric CRISPR Cures

So that, I think, is a great substrate for starting a new center.

Ground Truths
Priscilla Chan & Jennifer Doudna: New Center for Pediatric CRISPR Cures

And so maybe back to you, Priscilla, as to what your vision was when you're working with Jennifer and IGI to go through with this.

Ground Truths
Priscilla Chan & Jennifer Doudna: New Center for Pediatric CRISPR Cures

Yeah, well, it's pretty remarkable because here you have incurable, ultra rare diseases.

Ground Truths
Priscilla Chan & Jennifer Doudna: New Center for Pediatric CRISPR Cures

If you can help these babies, you know, just think of what this could do in a much broader context.

Ground Truths
Priscilla Chan & Jennifer Doudna: New Center for Pediatric CRISPR Cures

I mean, there are a lot of common diseases have their roots with some of these very rare ones.

Ground Truths
Priscilla Chan & Jennifer Doudna: New Center for Pediatric CRISPR Cures

So how do you see going forward, Jennifer, as to

Ground Truths
Priscilla Chan & Jennifer Doudna: New Center for Pediatric CRISPR Cures

where you see Berkeley, Gladstone, UCSF.

Ground Truths
Priscilla Chan & Jennifer Doudna: New Center for Pediatric CRISPR Cures

I'm envious of you all up there in Northern California, I have to say.

Ground Truths
Priscilla Chan & Jennifer Doudna: New Center for Pediatric CRISPR Cures

We'll pull this off.

Ground Truths
Priscilla Chan & Jennifer Doudna: New Center for Pediatric CRISPR Cures

How will you get the first similar case to KJ Muldoon going forward?

Ground Truths
Priscilla Chan & Jennifer Doudna: New Center for Pediatric CRISPR Cures

Do you think it's possible to go any faster right now than the six months that it took for KJ?

Ground Truths
Priscilla Chan & Jennifer Doudna: New Center for Pediatric CRISPR Cures

Yeah.

Ground Truths
Priscilla Chan & Jennifer Doudna: New Center for Pediatric CRISPR Cures

Yeah, and I also would note, as you both know well, this administration is really keen on genome editing, and they've had a joint announcement regarding their support.

Ground Truths
Priscilla Chan & Jennifer Doudna: New Center for Pediatric CRISPR Cures

And in my discussions with the FDA commissioner, this is something I'm very excited about.

Ground Truths
Priscilla Chan & Jennifer Doudna: New Center for Pediatric CRISPR Cures

So this timing of the new center

Ground Truths
Priscilla Chan & Jennifer Doudna: New Center for Pediatric CRISPR Cures

for pediatric CRISPR cures is aligned with the current administration, which is good to see.

Ground Truths
Priscilla Chan & Jennifer Doudna: New Center for Pediatric CRISPR Cures

It's not always the case.

Ground Truths
Priscilla Chan & Jennifer Doudna: New Center for Pediatric CRISPR Cures

Now, going back, Priscilla, to your point that not just for the liver, because delivery has been an issue, of course, and if we're going to try to get after a lot of these really rare diseases, it's going to go beyond the liver.

Ground Truths
Priscilla Chan & Jennifer Doudna: New Center for Pediatric CRISPR Cures

So this is also an exciting new dimension of the center, as you said, to go after the bone marrow for

Ground Truths
Priscilla Chan & Jennifer Doudna: New Center for Pediatric CRISPR Cures

hematopoietic cells, perhaps other organs as well?