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George Church

๐Ÿ‘ค Person
710 total appearances

Appearances Over Time

Podcast Appearances

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

So there's all kinds of things you can do in biology where you're working at a very high programming level is a way of thinking about it.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

Pushing us to a new level of intelligence is going to be very challenging and maybe not even urgent.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

To some extent, actualizing the people that we currently have would be quite, you know, just getting them

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

all up to whatever speed they wanna be up to within the range that's been demonstrated.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

So like some people are gonna wanna be like Einstein, some people won't.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

Some people wanna be healthy all the time, unlikely, but some people might not.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

Some people might wanna live to 150.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

Some people might wanna die at 80.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

But if you give them that range, that capability, what if we had 8 billion super healthy,

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

Don't need to worry about food and drugs.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

Super healthy, Einstein level of intelligence, education level, best we can come up with.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

That would be a completely different world.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

I would say mostly GWAS for humans.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

maybe for animals in general, followed for animals with synthetic biology, you know.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

And the smaller and the cheaper and faster replicating, the more experiments you can do.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

So, you know...

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

I don't want to overemphasize how single genes can do these amazing things, but there's also the possibility that multiple genes can be hypothesized and tested quickly.

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

So for example, I mentioned earlier, what's the minimum number of transcription factors it takes to turn a stem cell into a neuron?

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

Well, there's a bunch of recipes where you can do it with one, right?

Dwarkesh Podcast
George Church โ€” A Billion Years of Evolution in a Single Afternoon

Maybe you want a specific neuron, you might need a few more.