Heather Whitson
speaker
81 appearances
1 recordings
1 series
first heard Dec 2023
last heard Dec 2023
Heather Whitson’s voice in public audio — every appearance, attributed to the second.
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The problem is, I think we have an obligation to the living humans today.
To recognize that that's a sea change from how most of the world thinks of the word Alzheimer's disease.
And and by by rushing this into sort of clinical practice and suddenly saying people that have
positive amyloid based on an imperfect biomarker, especially, now they have Alzheimer's disease.
I think we're opening.
Massive potential for harm and distress and predatory.
um practices upon these people.
And that's where I sort of just want to pump the brakes on taking what I see as a very helpful research framework.
Rushed into clinical care.
you're talking about intervention studies, and there's a whole set of studies that I also want to see, which is just population studies of these biomarkers and observational populations of young people to understand how many of them have these biomarkers.
Yeah.
And and I I guess I wanna can I make one more point on this topic?
So I I completely applaud skepticism and paying attention to where the money's coming from and who's getting the money and what people's conflicts are.
Completely applaud it.
A little bit in defense of the field, though.
I want to also say that I think that some of it is motivated by.
genuine belief out there that our best chance to help people is to detect them earlier and earlier in the disease process and before they have symptoms.
And so, you know, and I I think all of the, you know, again with cautions to cooled analyses and sub-analyses and comparing across across different trials, but if you take all of the signs, they all point in the same way, which is that the earlier in the disease process and before
as as early in symptomatology as possible is the time that you get the best benefit.
From any of the
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