Menu
Sign In Search Podcasts Charts People & Topics Add Podcast API Blog Pricing

James Smith

๐Ÿ‘ค Speaker
922 total appearances

Appearances Over Time

Podcast Appearances

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

No, I think all the work that's happened already for therapeutic purposes doesn't pose any special risk.

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

It poses the same risks as any new drug development.

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

So it might have

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

things that you didn't predict would happen yeah but it can't self-replicate and so i don't think it's particularly dangerous where the line should be between those and mirror life is a really difficult question and one of the key open questions i think at the moment in the discussion around mirror life that we'll probably talk about in a minute

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

I think the risks from making mirror life would just be far greater than the benefits that you'd get from being able to develop better countermeasures.

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

But even more than that, we've already talked about how mirror experiments can tell you a lot about mirror life.

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

So if you want to develop a countermeasure against mirror life, one way to do that is to make mirror life, and this is the way that I don't endorse, is to make mirror life and then test countermeasures against it.

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

The other thing that you could do is use normal life as a model organism and make mirror countermeasures against normal life.

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

That means if there was ultimately a mirror life outbreak, you could just take the mirror of the countermeasures that you've developed and scale that up instead.

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

In a way, we know a lot about myrobacteria and how they would behave because physics tells us exactly what would happen.

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

It would behave in the same way as normal life in isolation.

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

And that's a really unusual property.

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

We can't usually reason so effectively about something that doesn't yet exist.

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

But I think that reduces the benefit of going ahead and making it.

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

And some people think...

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

No, I don't think so.

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

But the reason for that is

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

The type of mirror life that we're talking about here, that all the analysis that's been done is focused on, is an exact mirror of life on Earth.

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

It's not something that would have some mirror components and look a bit like what we have on life on Earth, because the special risks come from the fact that mirror life is already well adapted to living on Earth, because it gets to benefit from all this evolutionary history.

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

It's vanishingly unlikely that an exact mirror of life on Earth would evolve on a different planet.