Jason Karlawish
speaker
1,378 appearances
5 recordings
1 series
first heard Feb 2021
last heard Dec 2023
Jason Karlawish’s voice in public audio — every appearance, attributed to the second.
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Appearances
Well no you you no, you you you have the disease because you required treatment.
So I think I mean Heather, you may have please weigh in.
Uh I think this is what the field still needs to figure out.
I think we're we're walking into an area that I think we haven't talked about, which we ought to, uh, which is the public health implications of a redefinition of disease.
On counting the disease.
And and claiming what the burden of it is.
And I do think that that needs some discussion.
So today
The way we say
count Alzheimer's is still the the figures that that are uh put forward by NIA and the Alzheimer's Association is reliant on individuals having some c eval evidence of cognitive impairment.
The Alzheimer's
that that that number relies on having at least MCI based on the the data they use from the Chicago study.
Um, if you define the disease on the basis of amyloid alone and you want to count Alzheimer's disease, you obviously would start you would I I don't know, go to the HRS data set and look at, you know, pooled bloods from that and test them for amyloid and you could come up with an estimate of the prevalence of Alzheimer's, it will be a dramatically larger number, which I guarantee will make headlines.
But it's a very different Alzheimer's than the Alzheimer's that they has preoccupied America's attention, has preoccupied policymakers' attention.
And the worry I have is is just that the misinterpretation of that number.
And almost a creation of constituencies in the plural with Alzheimer's.
Well, yeah, you've got the beta amyloid Alzheimer's and otherwise are fine.
I've got the Alzheimer's that has me needing someone to manage my checkbook.
I don't drive anymore and you know, I um uh rely on someone else to handle my meals.
Those are two very different ways of living with the disease.
Showing 141–160 of 1,378 · page 8 of 69
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