Jodi Duval

speaker

654 appearances 9 recordings 1 series first heard Jun 2026 last heard 3d ago

Jodi Duval’s voice in public audio — every appearance, attributed to the second.

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recordings per month · last 12 months

Recordings per month over the last 12 months — 9 in all, peaking in Jul 2026 with 4.

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And the functional root cause of cellular health is membrane integrity.

So root cause is not enough if the root question is still disease.

Pathogenesis is root causes of disease, and salutagenesis is the root causes of health.

So to understand this, we have to then look at

That inner membrane or inner mitochondrial membrane, the IMM.

This is where the oxidative phosphorylation occurs, and the electron transport chain pumps protons from the matrix into the intermembrane space.

So this creates that electrochemical gradient, a biological battery.

But then the lipid composition of this membrane is 90% phospholipids.

So the most abundant of these is phosphodylcholine, or PC.

As we age, the natural synthesis of this PC declines.

And so the way this was elegantly demonstrated in a landmart study published in Nature Communications by Dr.

Maria's team at the Leibitz Institute of Aging in Germany.

So they discovered that when

T C levels drop.

The mitochondrial membrane loses their flexibility.

They fragment.

And then they can no longer undergo the mitochondrial fusion, which is the vital process where mitochondria merge and to share that DNA.

So signaling molecules and repair components, without PC and all of these processes, the membrane physically degrades.

So the protons begin to leak directly back across the bilayer and bypassing the ATP synthase pump.

So this battery is then short-circuited.

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