John Stanford
speaker
1,479 appearances
11 recordings
1 series
first heard May 2026
last heard 13 Aug
John Stanford’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 11 in all, peaking in Jul 2026 with 4.
Appearances
It can damage cancer, but it also damages healthy tissue often.
A targeted antibody can be designed more like a guided system.
Find a particular feature on a cell, attach to it, and block its activity, or alert the immune system to attack.
Today monoclonal antibodies are used not just in cancer, but inflammatory diseases, asthma, osteoporosis, high cholesterol, infectious disease, and many other conditions.
At the same time, combinations of antiviral drugs transformed another once terrifying diagnosis.
In the early years of the AIDS epidemic, people diagnosed with AIDS might expect to survive only a year or two.
By the mid-90s, though, researchers had developed highly active anti-retroviral therapy, drug combinations that attacked HIV at multiple points in its life cycle.
In the first year after these combinations,
Became the standard of care, AIDS-related deaths in the United States fell dramatically.
Today, people who are diagnosed with HIV can suppress the virus and live long, healthy lives.
And we may even be on the brink of a vaccine that prevents the spread of the disease altogether.
Another takeaway from scientists' reaction to the AIDS epidemic is that the greatest breakthroughs didn't come from one dramatic flash of inspiration.
At a time when treating the disease and figuring out which medicine might work had to be paired with manufacturing and process innovations that allowed that medicine to be made at scale.
These things happened not simultaneously and not even necessarily collaboratively, but they show what can be done when everyone is working together, building on the successes of one another.
The 1990s also helped launch one of the most ambitious scientific projects ever, sequencing the human genome.
The Human Genome Project was expected to take 15 years and cost roughly $3 billion, but it was completed ahead of schedule in 2003.
And for the first time, scientists had a reference map of the approximately 3 billion letters in our human DNA.
That mapped moved medicine towards a new question.
Instead of asking only what disease does this patient have, researchers could increasingly ask, what is driving this disease in this particular patient?
The era of genomic medicine had begun.
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