Jonathan McRae

speaker

4,627 appearances 33 recordings 1 series first heard Apr 2026 last heard today

Jonathan McRae’s voice in public audio — every appearance, attributed to the second.

Trend

recordings per month · last 12 months

Recordings per month over the last 12 months — 33 in all, peaking in Aug 2026 with 9.

Appearances

newest first · ▶ plays the moment

Futureproof with Jonathan McCrea · Could ozempic cure addiction? · 20 Sep 2026 podcast

We have not talked about this combination. voice-verified

So first off, you're an expert in addiction. voice-verified

Where did you get the idea to look at drugs that we normally associate with obesity and diabetes? voice-verified

Talk me through just GLP-1s at the moment. voice-verified

So, you know, people have heard of Ozempic and WeeGovie and so on. voice-verified

What is the mechanism by which they work, they help people lose weight? voice-verified

What is going on in the brain or in the gut that helps them do that? voice-verified

Right. voice-verified

Let's talk a little bit about addiction and how addiction works. voice-verified

So addiction has both a physical and a neurological component, right? voice-verified

You would be one of the leading experts and voices in America on addiction. voice-verified

How is it that we still don't fully understand what makes someone crave something in a way that is harmful to them? voice-verified

So talk to me about this idea of using what we use as appetite suppressant drugs to also suppress cravings from addiction. voice-verified

What work have you done in this area and do you think it's a genuine area that holds promise? voice-verified

I mean, there's so many positives to that. voice-verified

And of course, if you're a drug manufacturer, this would be an absolute goldmine, right? voice-verified

Because if you can prove that this works, the devastation, the cost, financial cost that someone living with addiction causes, not just them, but many people around them, the idea that you could actually treat this is really exciting. voice-verified

So talk to me about the mechanism and the work that you've been doing so far. voice-verified

dopamine voice-verified

You know, we've often talked about, you know, the reliability of animal models, but certainly when it comes to addiction and addictive-like behaviour, you know, we have methods of making an animal addicted to something so we can test addiction. voice-verified

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