José Díaz-Balart

It's as if she just vanished.

You're acting like a detective here.

She moved across the world looking for a new life.

Soon, friends in law enforcement were looking for her.

I'm Lester Holt, and this is Dateline.

What would you do if your best friend suddenly disappeared?

If a woman who loved to sing and laugh and make plans simply vanished?

What if it was your job to find her?

You really are in a race against time.

For these three women, there was only one option.

Sana Ramo first met 39-year-old Anna Kanesevich at a local happy hour in Fort Lauderdale, Florida.

It's almost as if you clicked almost immediately.

As they got to know each other, Sana learned that Ana was a successful businesswoman who had the freedom to go where she pleased.

And the place she really wanted to go was Madrid, Spain.

She was drawn to the way the city pulses with culture, history, and light, loved the passionate nature of its people.

The winding cobblestone streets, she believed, could be the stepping stones for a simpler, more authentic life.

So in December of 2023, Sana said goodbye to Ana as she packed up and moved from Fort Lauderdale to Madrid.

She checked in with Sana almost every day.

This is a happy time for her.

Elisa Romero was one of Ana's best friends in Madrid.