Julia Belluz
speaker
540 appearances
2 recordings
2 series
first heard Feb 2026
last heard 8 May
Julia Belluz’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 2 in all, peaking in May 2026 with 1.
Appearances
So as researchers who are working on this are trying higher and higher doses to help people with diabetes get more and more benefit, they start to discover these weight loss results in the trial.
So people start to spontaneously lose weight.
And then later we're finding all these slew of other benefits that no one would have predicted.
No pharma company would have bet on this.
We're only at the beginning of what's been called this Ozempic era.
I think we're really just at the beginning of discovering the benefits and the harms of these drugs.
So it depends on the drug, but we're talking like 15 to 30%.
So it's the first time we have a drug that really rivals the more effective types of bariatric surgery.
The key point is that it's turning down appetite.
So it's not ramping up metabolism or energy burn.
And the idea was that this is a gut hormone.
That's the thing that a lot of people focused on.
It's released after eating and it helps people signal satiety.
It helps them feel full and know that they've eaten.
And we're just giving a really souped up version of this gut hormone.
And it turns out that actually you need to stimulate the brain GLP-1 system to get the weight loss effects.
So you only interfere with appetite once you reach this brain GLP-1 system.
Yeah, the way we describe it in the book, we use this analogy of breathing.
So if I tell you, like, take control of your breath right now, like breathe more slowly or breathe more quickly or hold your breath, you can take control for short periods of time, but eventually physiology takes over.
And the same thing is true of what we eat.
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