Madeleine Finlay
speaker
2,527 appearances
37 recordings
2 series
first heard Apr 2026
last heard 5d ago
Madeleine Finlay’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 37 in all, peaking in Aug 2026 with 8.
Appearances
Imagine a pill for youth.
Not just one that slows ageing, but actually turns back the clock.
A trial has begun that aims to restore damaged eye cells to a more youthful state, hopefully improving sight.
If it works, it could potentially be developed for other organs, or maybe even our whole bodies.
So today, how researchers are trying to reverse biological time.
From The Guardian, I'm Madeleine Finlay, and this is Science Weekly.
Ian, back in June, a US biotech company called Life Biosciences announced that a human participant had received a world first treatment for age-related eye disease.
And this is essentially all about making research
retinal cells young again.
And it's a really big milestone for this concept of cellular rejuvenation.
And as you might imagine from the name, this is also something that the longevity community are really excited about, right?
So before we get to the trial, I think we need to go back to some first principles.
Just spell out for me, what happens as our cells get older?
Right, OK, so explain those epigenetic changes to me.
And so the fact that the epigenome can change or it can be changed by environmental factors leads to this kind of idea that maybe you can purposefully change the epigenome to change what the cell is doing or how it operates.
OK, Ian, so there's this idea that you can potentially sort of blow off our biological dust.
How do you do it in the lab or how are scientists trying to do it in the lab?
Don't think about it too closely.
So you can apply these proteins, these factors to an adult cell, a skin cell, a liver cell, and it's going to turn that cell back into a pluripotent stem cell.
It sounds like scientists have done this successfully in the lab in a Petri dish.
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