Madeleine Finlay
speaker
2,579 appearances
38 recordings
2 series
first heard Apr 2026
last heard today
Madeleine Finlay’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 38 in all, peaking in Sep 2026 with 8.
Appearances
retinal cells young again.
And it's a really big milestone for this concept of cellular rejuvenation.
And as you might imagine from the name, this is also something that the longevity community are really excited about, right?
So before we get to the trial, I think we need to go back to some first principles.
Just spell out for me, what happens as our cells get older?
Right, OK, so explain those epigenetic changes to me.
And so the fact that the epigenome can change or it can be changed by environmental factors leads to this kind of idea that maybe you can purposefully change the epigenome to change what the cell is doing or how it operates.
OK, Ian, so there's this idea that you can potentially sort of blow off our biological dust.
How do you do it in the lab or how are scientists trying to do it in the lab?
Don't think about it too closely.
So you can apply these proteins, these factors to an adult cell, a skin cell, a liver cell, and it's going to turn that cell back into a pluripotent stem cell.
It sounds like scientists have done this successfully in the lab in a Petri dish.
But what about in living animals?
How have those experiments gone?
Because I can't imagine that you would want to turn adult cells, all adult cells back into stem cells.
You know, you don't want instead of your liver, a big blob of stem cells.
So how have experiments gone?
Wow.
This sounds very complex.
It sounds very risky.
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