Marty Makary
speaker
939 appearances
6 recordings
5 series
first heard Jan 2026
last heard 13 May
Marty Makary’s voice in public audio — every appearance, attributed to the second.
Trend
recordings per month · last 12 monthsRecordings per month over the last 12 months — 6 in all, peaking in Jan 2026 with 4.
Appearances
And we see online pharmacies doing the same thing now as if they're exempt and they can make claims about benefits with no mention of side effects.
Animal testing is not a very good model to predict how well a drug is going to do in humans.
As a matter of fact, 90% of drugs that pass animal testing do not pass human safety and efficacy testing.
So it's not a good predictor, and it goes both ways.
Sometimes drugs are rejected because they don't pass animal studies, but then they are safe in humans.
Aspirin
would have never been approved based on animal testing studies.
But it turns out aspirin is a powerful medication for humans.
So there's a group of treatments and potential cures that have been essentially halted at the animal testing stage when now we have other ways to test how it works in humans.
Computational modeling
and what we call organ-on-a-chip technology, whereby cells are grown in a laboratory and the drug is given to those cells in the laboratory to see how the cells respond, those are more predictive than traditional animal testing for a series of drugs.
There's a lot of tradition when it comes to the FDA and regulatory policy.
And investors have gotten used to the predictability of the requirements of the FDA.
We've said we're going to take massive steps in our roadmap to eliminate animal testing requirements.
category by category, starting with monoclonal antibodies where the computational modeling predictive value is amazing, where organ-on-a-chip technology is very mature, and where the animal testing used is excessive.
The average monoclonal antibody uses 144 chimpanzees.
From an ethical standpoint, I personally do not believe that God created these animals on planet Earth for us to subjugate and torture with this testing.
If somebody comes with an idea to the FDA, we'll discuss it.
We will discuss it.
But we do follow the law, and the FDA remains an independent scientific organization.
Showing 281–300 of 939 · page 15 of 47
← Previous
Next →