Matt Walsh

This belief shapes how people understand their moods.

This review suggests that the huge research effort based on the serotonin hypothesis has not produced convincing evidence of a biochemical basis to depression.

This is consistent with research on many other biological markers.

We suggest it is time to acknowledge that the serotonin theory of depression is not empirically substantiated.

In the psychiatric world and the medical industry generally, that is like a nuclear bomb exploding, or it should be.

The whole basis for all these drugs that we're putting millions of people on

Almost everything we've said about depression, our whole basis for even claiming it's a physical disease in the first place, is wrong.

There's no evidence for it.

But what's happened since this paper was published in 2022?

Nothing.

Nothing has happened.

The rate of SSRI prescriptions has not slowed down at all.

According to all the data I've seen, there has not been a drop in SSRI prescriptions at all.

People are still taking them, even though doctors admit they have no idea what these drugs are doing to the brain.

Let me state that again, because it's important you understand this.

The entire medical basis for prescribing SSRIs has been debunked, and yet doctors are still prescribing them at the same or even maybe higher rates.

Now, does that mean that SSRIs are totally ineffective?

No, actually, it's worse than that.

They do have an effect.

It's just that the effect is often quite negative.