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Max Lugavere

👤 Speaker
8803 total appearances

Appearances Over Time

Podcast Appearances

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

But I think chronic use is very bad from a cardiorespiratory standpoint.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

So using it regularly, I think, is very bad.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

Using it from like on a like acutely, we don't have the data to say that that has, you know, any significant negative downside.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

It's not a carcinogen.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

And I'm talking about like pouches, like like just nicotine.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

I'm not talking about combustible pouches or patches.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

Yeah.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

Exactly.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

Carcinogens and volatile organic organic compounds and the like.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

There is some data like very tenuous at this point, data suggesting that nicotine might play a protective role against Parkinson's disease.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

There is this weird, super paradoxical line of research linking cigarette smoking to a reduced risk of Parkinson's disease, which is very odd because smoking is a risk factor for everything else, pretty much Alzheimer's disease and the like.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

But for some reason, smokers have a lower risk of Parkinson's disease.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

And there have been some mechanistic like animal studies linking nicotine specifically to a sort of, you know, anti-inflammatory antioxidant ability in the brain that might help it, you know, in a way defend itself against toxic exposure.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

We don't have like solid human data yet to say that with certainty.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

So I want people to be really careful.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

I'm not saying that nicotine is good for the brain.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

We need more data to say that for sure.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

And I do think that there are very significant cardiovascular downsides, like chronic use of nicotine

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

you know, increases heart rate, it increases blood pressure, you just don't want to do it chronically, I think.

Culture Apothecary with Alex Clark
Prevent Alzheimer’s & Dementia Before It Starts | Max Lugavere

And nicotine is a highly addictive chemical.