Melanie Wilkinson

speaker
39 appearances 1 recordings 1 series first heard Sep 2026 last heard 10 Sep

Melanie Wilkinson’s voice in public audio — every appearance, attributed to the second.

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Recordings per month over the last 12 months — 1 in all, peaking in Sep 2026 with 1.

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Now no organ needs that buffer more than the brain.
Your brain is only 2% of your body mass, but it's an energy hog.
It uses roughly 20% of your daily calories.
And as we age or when diseases like Alzheimer's potentially set in, the brain's energy metabolism starts to struggle.
Which raises the essential question: if creatine can enlarge that energy buffer, can it support the brain when it's under metabolic stress?
Which goes back to that original question.
Question, could creatine prevent dementia?
Now, unfortunately, we cannot say that just yet, but there are some preliminary findings that are promising.
There's the most recent one, a 2025 pilot study of 20 Alzheimer's patients, showed that 20 grams of creatine daily for eight weeks boosted brain creatine levels by 11%.
More importantly, participants saw significant improvements in things like working memory and attention.
Now this was a single arm study.
So every participant took creatine and there was no placebo working control group.
And without that kind of control group, we cannot establish cause and effect.
But I would say this study is still a huge catalyst to establish further, more rigorous trials within this area.
Now, interestingly, when it comes to other areas of brain health beyond dementia, the evidence is probably slightly further ahead.
So a 2024 meta-analysis found supplementation improved memory, attention, and processing speed.
Other studies show it protects cognitive performance during sleep deprivation.
And in psychiatry, early trials have suggested it it may boost the response to antidepressants in women with major depression.
So the role of creatine and brain health is a genuinely really exciting area of research and I'm confident we'll see more and more promising studies coming through.
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