Michael Levin

speaker
450 appearances 1 recordings 1 series first heard May 2025 last heard May 2025

Michael Levin’s voice in public audio — every appearance, attributed to the second.

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But that's not what this process is actually doing.
If you start to interfere with it, you will see that it works actually really hard.
It's not an open loop of process.
It it tries really hard to get to a particular outcome.
So that means and and the thing that's really hard about the standard story is that if you wanted to do, let's say, regenerative medicine and you wanted to I I, you know, this is the this is the wrong outcome.
I want a different outcome.
Or like what what Terry was just saying about evolution, like going backwards, right?
and and and figuring out how to encode it.
It becomes really hard if all you have is this feed forward that like that that inverse problem is j is is not solvable in general.
But if you have a component where what I have is a self-organizing pattern, it's self-organizing because of some math and also because of the kinds of ion channels that evolution has provided us with.
So it's an excitable medium.
And then of course, also, you know, touring patterns of chemical signals and biomechanics and everything else.
Um the math will give us a a a set point that for a period of time will allow us to get to a particular point and
w serves as a really tractable control knob for when you want to make two headed worms or fix birth defects.
So that's one of the things we we we we work out now is um very simple stimuli that uh that that repair very complex um uh defect.
For example, notch mutations, right?
If you mutate notch in the in the the brain is just completely wrecked.
But the first thing that gets wrecked from that is the bioelectrical pattern that dictates the shape and size of the brain.
And if you force the correct pattern, you can have perfectly normal tadpoles with behavior indistinguishable from control, like learning.
They have learning indistinguishable from controls, even though that dominant notch overactive notch mutant is still there.
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