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Michael Levin

๐Ÿ‘ค Speaker
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4080 total appearances
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Podcast Appearances

Lex Fridman Podcast
#486 โ€“ Michael Levin: Hidden Reality of Alien Intelligence & Biological Life

life form we call a xenobot.

Lex Fridman Podcast
#486 โ€“ Michael Levin: Hidden Reality of Alien Intelligence & Biological Life

And it's this self-motile little thing that has cilia covering its surface.

Lex Fridman Podcast
#486 โ€“ Michael Levin: Hidden Reality of Alien Intelligence & Biological Life

The cilia are coordinated, so they row against the water and then the thing starts to move and has all kinds of amazing properties.

Lex Fridman Podcast
#486 โ€“ Michael Levin: Hidden Reality of Alien Intelligence & Biological Life

It has different gene expression, so it has its own novel transcriptome.

Lex Fridman Podcast
#486 โ€“ Michael Levin: Hidden Reality of Alien Intelligence & Biological Life

It's able to do things like kinematic self-replication, meaning make copies of itself from loose cells that you put in its environment.

Lex Fridman Podcast
#486 โ€“ Michael Levin: Hidden Reality of Alien Intelligence & Biological Life

It has the ability to respond to sound, which normal embryos don't do.

Lex Fridman Podcast
#486 โ€“ Michael Levin: Hidden Reality of Alien Intelligence & Biological Life

It has these novel capacities.

Lex Fridman Podcast
#486 โ€“ Michael Levin: Hidden Reality of Alien Intelligence & Biological Life

And we did that.

Lex Fridman Podcast
#486 โ€“ Michael Levin: Hidden Reality of Alien Intelligence & Biological Life

And we said, look, here are some amazing features of this novel system.

Lex Fridman Podcast
#486 โ€“ Michael Levin: Hidden Reality of Alien Intelligence & Biological Life

Let's try to understand where they came from.

Lex Fridman Podcast
#486 โ€“ Michael Levin: Hidden Reality of Alien Intelligence & Biological Life

And some people said, well, maybe it's a frog specific thing.

Lex Fridman Podcast
#486 โ€“ Michael Levin: Hidden Reality of Alien Intelligence & Biological Life

You know, maybe this is just something unique to frog cells.

Lex Fridman Podcast
#486 โ€“ Michael Levin: Hidden Reality of Alien Intelligence & Biological Life

And so he said, okay, what's the furthest you can get from frog embryonic cells?

Lex Fridman Podcast
#486 โ€“ Michael Levin: Hidden Reality of Alien Intelligence & Biological Life

How about human adult cells?

Lex Fridman Podcast
#486 โ€“ Michael Levin: Hidden Reality of Alien Intelligence & Biological Life

And so we took cells from adult human patients who were donating tracheal epithelia for biopsies and things like that.

Lex Fridman Podcast
#486 โ€“ Michael Levin: Hidden Reality of Alien Intelligence & Biological Life

And those cells in, again, no genetic change, nothing like that.

Lex Fridman Podcast
#486 โ€“ Michael Levin: Hidden Reality of Alien Intelligence & Biological Life

They self-organized into something we call anthrobots, again, self-multi-little creature, 9,000 different gene expressions.

Lex Fridman Podcast
#486 โ€“ Michael Levin: Hidden Reality of Alien Intelligence & Biological Life

So about half the genome is now different.

Lex Fridman Podcast
#486 โ€“ Michael Levin: Hidden Reality of Alien Intelligence & Biological Life

And they have interesting abilities.

Lex Fridman Podcast
#486 โ€“ Michael Levin: Hidden Reality of Alien Intelligence & Biological Life

For example, they can heal human neural wounds.