Michael O'Reilly

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46 appearances 1 recordings 1 series first heard May 2026 last heard 22 May

Michael O'Reilly’s voice in public audio — every appearance, attributed to the second.

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Recordings per month over the last 12 months — 1 in all, peaking in May 2026 with 1.

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Good morning, David.

Thank you very much for the invitation to speak to you and your audience this morning.

So PMOS, as it's known, as of the last two weeks, is a hormonal condition that affects between probably 8 and 15% of all women.

It is associated with metabolic issues, and those metabolic issues are quite variable.

But most women with PMOS will have insulin resistance, which means that their body's insulin

doesn't work as well as it should to control blood sugars, and that puts them at risk of future type two diabetes.

But they will also have other hormonal disturbances like high testosterone levels in the blood.

And this kind of presents clinically in a multitude of ways.

So women with PMS will generally have irregular menstrual cycles.

That's due to ovulation not taking place every month as it should.

So some women with PCOS would only have two to three menstrual bleeds per year rather than 12, which would be the norm in the background population.

They can also develop issues related to high testosterone and they are many and varied as well.

They can have skin conditions like excess hair growth, which is medically termed hirsutism.

They can have very troublesome acne and even hair loss from the scalp or alopecia.

And many women with PCOS will live with overweight and obesity for a multitude of reasons.

And there are complex hormonal drivers of that from insulin to testosterone.

So how PMOS affects women?

a woman really is very variable, but that's kind of the spectrum of health issues that they can encounter.

Yeah, there's no question that it did, David.

So it would have, I think, led to delays in patients seeing the correct specialist.

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