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Mike Israetel

๐Ÿ‘ค Speaker
2772 total appearances

Appearances Over Time

Podcast Appearances

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

That great thing about what we talked about earlier with Dorian Yates and how he could do so few sets and get so many results is that 80-20 type of rule applies to almost everything else in the human body, including nutrition. So if you're getting enough protein regularly and you're getting enough calories to gain body weight, if you don't get really the muscle gains that you were expecting,

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

There aren't a lot of knobs and levers for us to pull that are going to get these enormous results. That's kind of the situation for nutrition. But consistency is, I cannot say enough things about. Because you ask people, hey, how's your diet? Especially if you're a personal trainer or diet coach.

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

There aren't a lot of knobs and levers for us to pull that are going to get these enormous results. That's kind of the situation for nutrition. But consistency is, I cannot say enough things about. Because you ask people, hey, how's your diet? Especially if you're a personal trainer or diet coach.

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

There's this kind of halo effect situation where they want to be seen as a good person and diligent and worthy of your time. So, well, yeah, you know, like breakfast, I'll have egg whites. And for lunch, I'll have a chicken sandwich. And for dinner, it's usually a piece of fish. And then I have a protein shake and go to sleep. Shut up, Bob. That's one day a week, you lying asshole.

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

There's this kind of halo effect situation where they want to be seen as a good person and diligent and worthy of your time. So, well, yeah, you know, like breakfast, I'll have egg whites. And for lunch, I'll have a chicken sandwich. And for dinner, it's usually a piece of fish. And then I have a protein shake and go to sleep. Shut up, Bob. That's one day a week, you lying asshole.

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

And he's like, God damn it, you got me. Okay, that was Tuesday. But Wednesday, I don't think I ate anything until we closed that one business deal and I got really drunk with their CMO. It was a great time. I think we had chicken fingers, but honestly, I can't remember. Inconsistency, especially when you're older, especially when you have lots of stress from your professional endeavors.

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

And he's like, God damn it, you got me. Okay, that was Tuesday. But Wednesday, I don't think I ate anything until we closed that one business deal and I got really drunk with their CMO. It was a great time. I think we had chicken fingers, but honestly, I can't remember. Inconsistency, especially when you're older, especially when you have lots of stress from your professional endeavors.

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

Inconsistency is something that professional bodybuilders cannot afford. You for sure cannot afford it. Now, if you do everything right five or six days a week and one day is kind of meh, you'll do great. But if the good days are outnumbered by the, I sure hope my trainer doesn't find out about these days, you're not doing due diligence. So that's a big, big part of the equation.

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

Inconsistency is something that professional bodybuilders cannot afford. You for sure cannot afford it. Now, if you do everything right five or six days a week and one day is kind of meh, you'll do great. But if the good days are outnumbered by the, I sure hope my trainer doesn't find out about these days, you're not doing due diligence. So that's a big, big part of the equation.

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

And that kind of segue, if you'd like, into a conversation of sleep and stress management, all these other things that can also be the difference between lots of gains or no gains at all.

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

And that kind of segue, if you'd like, into a conversation of sleep and stress management, all these other things that can also be the difference between lots of gains or no gains at all.

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

So anabolic androgenic steroids are all derivatives of the testosterone molecule manipulated in various ways to accentuate some characteristics and de-emphasize other characteristics. They're typically taken by athletes in the competitive sphere, bodybuilders, physique athletes, and gym people who want a super physiological level of muscle mass. And

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

So anabolic androgenic steroids are all derivatives of the testosterone molecule manipulated in various ways to accentuate some characteristics and de-emphasize other characteristics. They're typically taken by athletes in the competitive sphere, bodybuilders, physique athletes, and gym people who want a super physiological level of muscle mass. And

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

Sometimes super physiologically low levels of body fat can come with that. And so they'll take anywhere between high end testosterone replacement therapy dose to 10 or 20 times that amount per week.

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

Sometimes super physiologically low levels of body fat can come with that. And so they'll take anywhere between high end testosterone replacement therapy dose to 10 or 20 times that amount per week.

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

for physiologic replacement is 40 milligrams twice a week or 80 milligrams a week so are you saying that there are people out there that would routinely take 800 to 1600 milligrams of testosterone in a week oh yeah sometimes that's not all testosterone it's other steroids and combination usually people take at least that replacement level of testosterone often more because testosterone does some really good things for health and general function and

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

for physiologic replacement is 40 milligrams twice a week or 80 milligrams a week so are you saying that there are people out there that would routinely take 800 to 1600 milligrams of testosterone in a week oh yeah sometimes that's not all testosterone it's other steroids and combination usually people take at least that replacement level of testosterone often more because testosterone does some really good things for health and general function and

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

tends to aromatize into estrogen quite readily, which is good because estrogen's cardioprotective, neuroprotective, increases your strength, helps your mood, tons. Sex drive, it actually increases your anabolism in the presence of androgenic steroids and testosterone. So estrogen by itself, not very anabolic.

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

tends to aromatize into estrogen quite readily, which is good because estrogen's cardioprotective, neuroprotective, increases your strength, helps your mood, tons. Sex drive, it actually increases your anabolism in the presence of androgenic steroids and testosterone. So estrogen by itself, not very anabolic.

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

Estrogen in the presence of testosterone is more anabolic than if you had all the testosterone in the world but were unable to aromatize to estrogen. And baseline low testosterone is often taken at somewhere between 250 milligrams a week and all the way up to a thousand milligrams a week, depending on how you're handling the side effects of that excess estrogen production at the higher levels.