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Mike Israetel

๐Ÿ‘ค Speaker
2772 total appearances

Appearances Over Time

Podcast Appearances

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

Estrogen in the presence of testosterone is more anabolic than if you had all the testosterone in the world but were unable to aromatize to estrogen. And baseline low testosterone is often taken at somewhere between 250 milligrams a week and all the way up to a thousand milligrams a week, depending on how you're handling the side effects of that excess estrogen production at the higher levels.

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

And that's usually taken as cipionate? Enanthate, cipionate. Some people prefer propionate if they inject every day. Enanthate and cipionate are by far the most commonly used, seemingly. Oftentimes, people inject differentially, but once daily injections seem to provide the smoothest curve.

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

And that's usually taken as cipionate? Enanthate, cipionate. Some people prefer propionate if they inject every day. Enanthate and cipionate are by far the most commonly used, seemingly. Oftentimes, people inject differentially, but once daily injections seem to provide the smoothest curve.

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

If you put in half a week's worth of super physiological testosterone at one time, your mood for the next several hours is curious.

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

If you put in half a week's worth of super physiological testosterone at one time, your mood for the next several hours is curious.

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

Most people feel something, but it's probably a normally distributed thing. population of experiences where some people just can't tell. Some people feel something for sure that they can describe, and some people have panic attacks and will never use again, or they are driven to extreme violent thoughts and extreme sexual thoughts and actions. And those folks are quite rare, but they do happen.

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

Most people feel something, but it's probably a normally distributed thing. population of experiences where some people just can't tell. Some people feel something for sure that they can describe, and some people have panic attacks and will never use again, or they are driven to extreme violent thoughts and extreme sexual thoughts and actions. And those folks are quite rare, but they do happen.

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

So there's a large distribution about which people can have experiences, but I'd say the median experience is the easiest way to understand the average effect of a high degree of anabolic steroids and for simplicity, testosterone. The psychology is to imagine that what is the average psychological proclivity of a female? What is the average psychological proclivity of a male?

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

So there's a large distribution about which people can have experiences, but I'd say the median experience is the easiest way to understand the average effect of a high degree of anabolic steroids and for simplicity, testosterone. The psychology is to imagine that what is the average psychological proclivity of a female? What is the average psychological proclivity of a male?

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

Different in many regards. And then you move the needle over one notch into a magical new gender called enhanced male. And you just typically exhibit more male-like patterns of thought and behavior than even males do. But males compared to females is the best way to figure that one out because if you're like,

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

Different in many regards. And then you move the needle over one notch into a magical new gender called enhanced male. And you just typically exhibit more male-like patterns of thought and behavior than even males do. But males compared to females is the best way to figure that one out because if you're like,

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

just know what a male pattern of behavior is like because you're a male, you're like, what the hell is it like to be more like me? Is it everything about me or it's not everything? We actually just had a recent video on the RP Strength channel. I think it's called Roid Rage is Real. We talk about like that steroids don't accentuate every quality you have, just the more masculine qualities.

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

just know what a male pattern of behavior is like because you're a male, you're like, what the hell is it like to be more like me? Is it everything about me or it's not everything? We actually just had a recent video on the RP Strength channel. I think it's called Roid Rage is Real. We talk about like that steroids don't accentuate every quality you have, just the more masculine qualities.

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

So what are the most masculine qualities? Again, this hits everyone a little bit differently, but on average, you become quieter. Men typically are not as expressive as women. You come to show fewer facial expressions of emotion. You don't process other people's emotions as well. You can't fine tune what they feel as much and you don't care as much. Less empathy.

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

So what are the most masculine qualities? Again, this hits everyone a little bit differently, but on average, you become quieter. Men typically are not as expressive as women. You come to show fewer facial expressions of emotion. You don't process other people's emotions as well. You can't fine tune what they feel as much and you don't care as much. Less empathy.

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

Way less empathy, all the way to similar levels of empathy, but on average, definitely less. And you become more likely to be irritable. You become more likely to have anger and aggressive sorts of thoughts. You become more attuned.

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

Way less empathy, all the way to similar levels of empathy, but on average, definitely less. And you become more likely to be irritable. You become more likely to have anger and aggressive sorts of thoughts. You become more attuned.

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

to the dominance hierarchy in general, and you become someone who thinks more about where you stack up in the dominance hierarchy in a way that you take affronts and slights more poorly than otherwise. So if someone on social media says you're a bad person, if you're not on a lot of testosterone, you're like, I'm just having a bad day. That's okay. We all have a bad day.

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

to the dominance hierarchy in general, and you become someone who thinks more about where you stack up in the dominance hierarchy in a way that you take affronts and slights more poorly than otherwise. So if someone on social media says you're a bad person, if you're not on a lot of testosterone, you're like, I'm just having a bad day. That's okay. We all have a bad day.

The Peter Attia Drive
#335 โ€’ The science of resistance training, building muscle, and anabolic steroid use in bodybuilding | Mike Israetel, Ph.D.

We need to rage out on someone. If you're on a lot of testosterone, you're more likely to be like, I wonder if he'd say that to my face. I wonder if he would be real quiet around me because he would know that I'm not someone to be messed with. weird, weird thoughts like that. Women almost never have thoughts like that. Men have regular thoughts like that in the right context.