Paul Saladino, MD

And I think what's going on here is accelerated membrane remodeling. So I'm just saying there are ways to do this. It's not easy. If a human wanted to accelerate the remodeling of your membranes, you could potentially eat a lower fat diet for 30, 60, 90 days. Understanding that a low fat diet is not super sustainable for humans.

But the other thing you could do is eat a very low polyunsaturated fat diet. You can look at the amount of linoleic acid in your diet and lower it. Even after avoiding seed oils, should you avoid olive oil? Olive oil can be 12 to 28% linoleic acid, right? Avocado oil can be 20% linoleic acid.

But the other thing you could do is eat a very low polyunsaturated fat diet. You can look at the amount of linoleic acid in your diet and lower it. Even after avoiding seed oils, should you avoid olive oil? Olive oil can be 12 to 28% linoleic acid, right? Avocado oil can be 20% linoleic acid.

But the other thing you could do is eat a very low polyunsaturated fat diet. You can look at the amount of linoleic acid in your diet and lower it. Even after avoiding seed oils, should you avoid olive oil? Olive oil can be 12 to 28% linoleic acid, right? Avocado oil can be 20% linoleic acid.

So I think you could accelerate the turnover of your membranes toward a lower linoleic acid membrane state by eating no olive oil, no avocado oil. Again, do it after Thanksgiving, right? And just lower in the amounts of linoleic acid in your diet. Beef tallow, 1% to 2% linoleic acid. Butter, 1% to 2% linoleic acid. Avocado oil, olive oil, 12 to 25. Canola, 25% linoleic acid. Soybean oil, 50%.

So I think you could accelerate the turnover of your membranes toward a lower linoleic acid membrane state by eating no olive oil, no avocado oil. Again, do it after Thanksgiving, right? And just lower in the amounts of linoleic acid in your diet. Beef tallow, 1% to 2% linoleic acid. Butter, 1% to 2% linoleic acid. Avocado oil, olive oil, 12 to 25. Canola, 25% linoleic acid. Soybean oil, 50%.

So I think you could accelerate the turnover of your membranes toward a lower linoleic acid membrane state by eating no olive oil, no avocado oil. Again, do it after Thanksgiving, right? And just lower in the amounts of linoleic acid in your diet. Beef tallow, 1% to 2% linoleic acid. Butter, 1% to 2% linoleic acid. Avocado oil, olive oil, 12 to 25. Canola, 25% linoleic acid. Soybean oil, 50%.

Corn oil, 45%. Grape seed oil, 55 to 60% linoleic acid. So if you focus on the low linoleic acid animal fats, the ones we've been told that are bad for us, you can accelerate the turnover of linoleic acid in your cell membranes. Butter especially, I believe, could be protective. And I'll tell you why. This is the second piece of this equation.

Corn oil, 45%. Grape seed oil, 55 to 60% linoleic acid. So if you focus on the low linoleic acid animal fats, the ones we've been told that are bad for us, you can accelerate the turnover of linoleic acid in your cell membranes. Butter especially, I believe, could be protective. And I'll tell you why. This is the second piece of this equation.

Corn oil, 45%. Grape seed oil, 55 to 60% linoleic acid. So if you focus on the low linoleic acid animal fats, the ones we've been told that are bad for us, you can accelerate the turnover of linoleic acid in your cell membranes. Butter especially, I believe, could be protective. And I'll tell you why. This is the second piece of this equation.

So lower fat oils or fats, animal fats that are much lower in linoleic acid, I believe this will accelerate the turnover of your membranes. There's a fatty acid, we were talking about this last night, called C15, pentadecanoic acid. Pentadecanoic acid. Most of the fatty acids in your cells are odd chain. saturated fats, C12, C14, C16, C18, lauric, myristic, palmitic, and stearic acid.

So lower fat oils or fats, animal fats that are much lower in linoleic acid, I believe this will accelerate the turnover of your membranes. There's a fatty acid, we were talking about this last night, called C15, pentadecanoic acid. Pentadecanoic acid. Most of the fatty acids in your cells are odd chain. saturated fats, C12, C14, C16, C18, lauric, myristic, palmitic, and stearic acid.

So lower fat oils or fats, animal fats that are much lower in linoleic acid, I believe this will accelerate the turnover of your membranes. There's a fatty acid, we were talking about this last night, called C15, pentadecanoic acid. Pentadecanoic acid. Most of the fatty acids in your cells are odd chain. saturated fats, C12, C14, C16, C18, lauric, myristic, palmitic, and stearic acid.

They're all odd chain. They're all even chain fatty acids, right? Odd chain fatty acids, C15 and C17 are starting to be understood, or we're looking at research. And there's research that suggests that C15 levels in your cell membranes can be protective against oxidative stress in your membrane.

They're all odd chain. They're all even chain fatty acids, right? Odd chain fatty acids, C15 and C17 are starting to be understood, or we're looking at research. And there's research that suggests that C15 levels in your cell membranes can be protective against oxidative stress in your membrane.

They're all odd chain. They're all even chain fatty acids, right? Odd chain fatty acids, C15 and C17 are starting to be understood, or we're looking at research. And there's research that suggests that C15 levels in your cell membranes can be protective against oxidative stress in your membrane.

So polyunsaturated fatty acid peroxidation, lipid peroxidation induced cell death is called ferroptosis. So apoptosis is programmed cell death, but ferroptosis is oxidative stress induced cell death. And C15 levels in your cell membranes protect against ferroptosis. So the ideal level of C15 in the study that I think was published in 2024

So polyunsaturated fatty acid peroxidation, lipid peroxidation induced cell death is called ferroptosis. So apoptosis is programmed cell death, but ferroptosis is oxidative stress induced cell death. And C15 levels in your cell membranes protect against ferroptosis. So the ideal level of C15 in the study that I think was published in 2024

So polyunsaturated fatty acid peroxidation, lipid peroxidation induced cell death is called ferroptosis. So apoptosis is programmed cell death, but ferroptosis is oxidative stress induced cell death. And C15 levels in your cell membranes protect against ferroptosis. So the ideal level of C15 in the study that I think was published in 2024

I think it's by Ven Watson is the main author, was 0.4 to 0.64% of your cell membrane is C15. Where do you get C15 in your diet? Butter and dairy. Dairy fats and butter are good sources of C15. In fact, they track so much that you can look at someone's C15 levels and tell how much dairy fat they're eating. Again, dairy fat being something that's been vilified, but you and I had raw milk.