Paul Turek
speaker
358 appearances
1 recordings
1 series
first heard Jun 2025
last heard Jun 2025
Paul Turek’s voice in public audio — every appearance, attributed to the second.
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Then when you outrun the woolly mammoth and you're behind a rock and you grab the berries and you catch a nap, boom, testosterone shoots up because it's rest and restore and you have to rebuild for the next run. How quickly do you think that occurs in humans? Days, easily. Chronic stress is it. We love acute stress. All species love acute stress. We love that starvation, intermittent fasting.
It's really healthy, but not low-level chronic stress, not connected to your computer, not your emails, not the workday that never ends. Terrible for us. And the best manifestation is erections because the erections will fall if you're under stress too. Penis has a mind of its own, according to Da Vinci. I had a guy come in, 25 in San Francisco, a startup guy.
And he comes in and says, I got to see you. I said, why? He said, I lost my erection yesterday. He's 25. I said, first time? He said, yes. I said, all right, come on in. So he comes in. And he's got his act together. It looks good. And I said, what happened? He said, I just lost my erection. It's never happened to me before. I think something's wrong. I said, okay, tell me about yourself.
He's just getting his A round of funding. He's traveling half a million miles a year. He sleeps three or four hours a night, if any. And he's constantly running. And I said, congratulations. Welcome to the human race. And she's like, what are you talking about? You're not impervious. Stress has its effects. So clearly, fertility. Oh, the great study was a moderate exercise, moderate exercise, man.
I wrote a blog on this called Can You Be Too Fit to Be Fertile? Moderate exercise went to extreme exercise, measured as two hours a day of VIO2, 80% maximum capacity. So pretty heavy workouts for 12-week periods. So moderate to extreme, and then back to moderate. Sperm counts fell by 40% when moderate to extreme, and testosterone fell by 50%, and then went back up.
And there's also military studies of men under acute stress during hell weeks in training where they were taking their testosterone and LHs, and they were dropping by about 50%. With severe stress. And that's okay for a day or two or a week. But when you're doing it chronically, we're not built for that, Peter. We're not built for chronic stress. That's a longevity issue.
All natural production.
And the two different classes are the LH and Clomid versus testosterone. So unlike testosterone shutting off the natural production, the LH, the ACG and the Clomiphene and Clomiphene will stimulate natural production. So you keep your testicular size, you maintain your fertility. Whereas the others, you're going to shrivel up your testicles and not maintain your fertility.
And you can't generate levels that you can with the exogenous testosterone with these. You'll never get to 3,000. You can't do that.
No signals, no gas to the engine. It's nuanced. There are formulations that are topical that are less potent that way, less inhibitory than injectables. So there are variations in the spectrum of exogenous testosterone that will maintain some of your fertility.
They're in the normal range more. What gives you side effects from testosterone, including sterility,
Testosterone, I can wait. And it was not available in America for 50 years. It was available in Europe. And a couple of researchers at UCLA, a husband-wife team, beautiful. What happened was we were worried when we took oral testosterone.
Yeah, we'd go to the liver.
Right, to the biliary system and go to the liver, cause liver cancer. So it was always verboten. Even though there was no evidence this was happening in Europe for 50 years. Yeah, not much. It's FDA approved. The EEA approved it. So this group came up with a way to get it metabolized through the lymphatics. So it could absorb through the lymphatic and never hits the liver. And it's really good.
I mean, there is a non-response rate of around 10%. So 10% of men, some like gels too, 15% won't respond. There's groups that won't respond that well, but it is really good.
Usually you don't want to do it right away too. So you want to give him a couple of weeks to stabilize hemostatically, right? But usually you can get pretty good levels because the half-life isn't that short. They say it peaks in five hours. So I don't know what the half-life is. Probably like 12, more like 12. You wouldn't dose it at 100% decay. You would dose it at 50%.
So he's probably not responding. We can check it at different times, but it's probably not much of a response.
It depends. I usually go to the mid-dose 298 twice a day. And then you can double it or whatever. I usually start out at not the lowest dose. And it depends what you're trying to solve too in the problem, right? If you want them, you're not going to get them to 800 or a thousand very easily. You can get them 400 to 600, 600, 700 pretty well, but no side effects.
I haven't seen anything that maybe a couple dozen men really well tolerated.
I've never, no one tolerates that.
Showing 161–180 of 358 · page 9 of 18
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