Philip Gehrman, PhD

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228 appearances 1 recordings 1 series first heard Jul 2026 last heard 8 Jul

Philip Gehrman, PhD’s voice in public audio — every appearance, attributed to the second.

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Speaking of Psychology · Rethinking sleep and mental health, with Philip Gehrman, PhD · 8 Jul 2026 podcast

And the the waste product that has been studied the most is the protein beta amyloid, which is of course thought to play.

A role in risk for Alzheimer's disease.

And so, for example, one night of total sleep deprivation in healthy individuals is associated with a 20% increase of this protein in the brain.

And so we're now thinking that chronically not getting a good night of sleep actually increases risk for dementia.

Now there is some some evidence that inflammation be may be one of the pathways for these associations.

Uh we know that difficulty sleeping is associated with increased inflammation.

And so uh so there's a lot of research.

It's a very hot area of research right now.

Chronic insomnia, meaning someone who's been having insomnia for three months or longer, is about 10 to 15% of the US population.

But about another 25 to 35% of people experience bouts of insomnia here and there, but maybe not continuous to the point where we would say, well, this is a chronic problem.

So if you add those up, it's roughly a third to a half of US adults are experiencing insomnia to at least some degree.

It's a huge problem.

And as far as the impact on mental health, I

And say there's kind of two components to that.

One is the next day effects.

So when I ask people, when you have not had a good night of sleep, how does that affect you during the day?

And one of the most common things I hear is I'm irritable.

I'm grouchy.

And so there's the the kind of the toll that it takes on just how you feel the next day in terms of your emotional and mental functioning difficulty concentrating.

with attention, things like that.

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