Professor Luke O'Neill

speaker
1,535 appearances 7 recordings 2 series first heard Apr 2026 last heard 3 Sep

Professor Luke O'Neill’s voice in public audio — every appearance, attributed to the second.

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recordings per month · last 12 months
3 · May OctJan 26AprJulnow

Recordings per month over the last 12 months — 7 in all, peaking in May 2026 with 3.

Appearances

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You can use antibiotics, of course, but the trouble is they come with other problems.
they can increase sort of all kinds of issues, really.
Overuse of antibiotics wouldn't be the best thing necessarily.
So even though we know some of these bacteria are a risk factor, you can take antibiotics to clear helicobacter, and that will indeed decrease your risk of gastric cancer, which is a good thing.
But it's a very active area.
Can we limit these bacteria to protect against cancer?
Now, the second area, though, is this.
Can the bacteria in your gut predict responsiveness to therapies we have already used?
Now, first of all, a big striking finding, again, just a few years ago, if you take a tumor from the gut, guess what?
It's full of bacteria.
Bacteria infiltrate tumors and they live inside them.
Can you believe it?
And they're sitting there and they're often promoting the tumor to grow in various ways.
We don't know what they're doing half the time.
It's a very active area.
What are these bacteria doing inside tumors?
And again, they're trying to find which particular species of bacteria can be found inside the tumor.
One famous one is called Peptostreptococcus that's been found in a few tumours.
So what these bacteria like is actually the lack of oxygen because very often inside a tumour there isn't much oxygen.
It's a big bulk of cells and the oxygen is lower inside there.
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