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Professor Salome Charalambous

๐Ÿ‘ค Speaker
240 total appearances

Appearances Over Time

Podcast Appearances

When Science Finds a Way
Is hope on the horizon for treating drug-resistant TB?

People have the drug-sensitive TB.

When Science Finds a Way
Is hope on the horizon for treating drug-resistant TB?

About 5% have the rifampicin-resistant TB.

When Science Finds a Way
Is hope on the horizon for treating drug-resistant TB?

And then this extensively drug-resistant TB becomes a much smaller proportion.

When Science Finds a Way
Is hope on the horizon for treating drug-resistant TB?

I can't tell you.

When Science Finds a Way
Is hope on the horizon for treating drug-resistant TB?

I think it's around probably 0.5% of all TB.

When Science Finds a Way
Is hope on the horizon for treating drug-resistant TB?

But if you have it, then it's a big problem, obviously.

When Science Finds a Way
Is hope on the horizon for treating drug-resistant TB?

Okay, so we are lucky enough that there is surveillance that goes on.

When Science Finds a Way
Is hope on the horizon for treating drug-resistant TB?

And in many countries, everybody who is first diagnosed with drug-resistant TB has additional testing done to make sure that they are not resistant to other drugs.

When Science Finds a Way
Is hope on the horizon for treating drug-resistant TB?

I think where the big problem comes in is making that first diagnosis.

When Science Finds a Way
Is hope on the horizon for treating drug-resistant TB?

As also mentioned by Dr. Ismail, that of people with drug-resistant TB, only half are actually picked up in the world.

When Science Finds a Way
Is hope on the horizon for treating drug-resistant TB?

And that's where our biggest gap is.

When Science Finds a Way
Is hope on the horizon for treating drug-resistant TB?

And then part of that is because of all the problems with diagnosing that we've already mentioned.

When Science Finds a Way
Is hope on the horizon for treating drug-resistant TB?

And so you have to diagnose TB to be able to then go forward and diagnose drug-resistant TB.

When Science Finds a Way
Is hope on the horizon for treating drug-resistant TB?

The first is increasing testing.

When Science Finds a Way
Is hope on the horizon for treating drug-resistant TB?

And so there have been many strategies where what we've tried to do is identify who is at risk and then test regardless of symptoms.

When Science Finds a Way
Is hope on the horizon for treating drug-resistant TB?

We call that targeted universal testing.

When Science Finds a Way
Is hope on the horizon for treating drug-resistant TB?

So testing people regardless of whether they have symptoms because they have a risk factor.

When Science Finds a Way
Is hope on the horizon for treating drug-resistant TB?

So being a minor or being in a prison is a risk factor for TB.

When Science Finds a Way
Is hope on the horizon for treating drug-resistant TB?

So testing more

When Science Finds a Way
Is hope on the horizon for treating drug-resistant TB?

Testing more people for TB is important.