Professor Trevor Graham
speaker
19 appearances
1 recordings
1 series
first heard Jan 2026
last heard 7 Jan
Professor Trevor Graham’s voice in public audio — every appearance, attributed to the second.
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Also in this podcast... In all those boxes in this room, like the crates in the Indiana Jones film, we think the answer might lie because we can treat the room like a time machine.
The number of cases of bowel cancer in young people that's defined by people under the age of 50 has more than doubled in the last few decades and we don't know the reasons why.
It is a worldwide thing so it's seen in countries around the world but the rate of increase differs between countries.
So in the UK the rates roughly doubled in the last couple of decades whereas in the US the rate of bowel cancer in young people is even higher than it is in the
We want to find out why, of course, and there are lots of possible reasons that could be causing this increase, but whatever the reason is, something's changed over the past few decades.
With my fantastic colleague, Professor Kevin Monaghan at St Mark's Hospital in London, that's the UK specialist bowel hospital, we're going to try and find out why.
St Mark's is a long-running hospital and it has discovered many of the important things about how bowel cancers grow.
And because of this proud history, they've been collecting samples for many, many years of bowel cancer specimens for more than a decade, we think.
And they're stored in the basement of the hospital in this wonderful room, which we think of as a treasure trove for research, really.
It's this room stacked floor to ceiling with boxes and
Reminds me a little bit of the end of the film Indiana Jones and the Last Crusade, you know, the warehouse, all those crates stored in there and somewhere in all those boxes in this room like the crates in the Indiana Jones film.
We think the answer might lie because we can treat the room like a time machine.
It documents what's happened over the past decades from the storing of these samples in this room.
Yes, exactly.
So whatever is causing this increase in bowel cancer in young people,
that thing itself must have increased over the past decades.
And so what we need is a time machine, you know, this is how we think of it, to be able to go back into those past decades and ask, well, what was rare in the past but is common now?
And so that's what we can do.
We can take samples from this fantastic archive and look at what's increasing over those decades compared to the present day.
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