Rhonda Patrick, Ph.D.

So the stronger the stimulus, the better the adaptation.

And

One of, just to kind of reiterate to people before we talk about the adaptations, you know, remember, one minute of vigorous physical activity was equivalent to almost eight times, right?

So eight minutes of moderate intensity physical activity.

That's a big difference.

And so...

One of the big adaptations here really comes down to increased blood flow.

It's just getting your blood pumping, moving, because what happens is this causes what's called shear stress on your vascular system, on the interior lining of the arteries.

And what shear stress is, is essentially just the friction of the blood flow against this interior lining of the arteries and the vascular system, right?

There's a friction there.

And so the stronger...

The exercise, the more vigorous the exercise, the faster your heart is pumping.

And that's why heart rate does come into this.

The more your blood flow is moving, right?

So you're getting a stronger, sheer stress.

And that is actually not a bad type of stress.

It's a good type of stress.

The sheer stress causes your endothelial cells lining your arteries to adapt automatically.

And in a way where it improves vascular function, it improves endothelial function, and it causes these endothelial cells to secrete beneficial molecules.

So one of those would be nitric oxide.