Rhonda Patrick, Ph.D.

So any way you look at it, you know, if you are in that higher cardiorespiratory fitness range, you are talking about, you know, a lifespan, life expectancy, you know, extension compared to if you were not in that range.

Yeah, and I think this is kind of important again, you know, I know people are going to be confused because we've talked about vigorous intensity exercise in such a different context than this study and also than the physical health guidelines.

And, you know, just going back to this study that Marty Gabala cited on the podcast a few years ago.

where you talked about, you know, 40% of people that are meeting the guidelines for moderate intensity physical activity, so that would be 150 minutes to 300 minutes a week, doing this, what is defined as moderate intensity activity, right?

They are unable to continue to improve their cardiorespiratory fitness, their VO2 max.

unless they're engaging in more vigorous types of exercise.

So again, in this regard, it seems as though the vigorous intensity exercises is not as vigorous as perhaps once thought.

What are your thoughts on that?

Yeah, more emphasis on on vigorous, I think, too, as well.

Okay, so some of the other adaptations, let's talk about, you know, the type two diabetes, lowering the new diagnosis of type two diabetes was very profound, right here, we're talking about almost vigorous intensity was almost 10 times as effective, right?

That's big.

So why is that?

And again, that is something that I've talked about a lot, and I did a podcast, like a solo cast on vigorous intensity exercise, and talked about, you know, why vigorous intensity seems to be really key for improving metabolic health.

When, you know, when you are working harder, when you're working your muscles harder, when you're basically forcing your muscles to

produce energy quicker, what ends up happening is you're not using your mitochondria all the time.

You're going to be using your mitochondria, but you're sometimes going to be making energy without them as well.

And so you're going to be making something called lactate as a quote-unquote byproduct, which is not necessarily a byproduct.

It's an active metabolite.

And why is that important?

Because lactate is not only a metabolite, in some ways it actually acts as a hormone.