Robert Fried

There's several of them.

We've studied all of them.

Progeria, is that one of them?

That's an example of one.

Cocaine syndrome is another example of an ataxia.

Where these kids age very rapidly, and some of them, they actually die of old age at the age of 12 or 13.

What we've seen in some of these conditions is non-detectable levels of NAD.

Wow.

So the relationship between NAD and the way the body ages is quite direct.

And what is aging?

Aging is the accumulation of damage at the molecular level, that's all it is, but the diminished ability to repair that damage.

Right, so by elevating NAD, you're improving the cell's ability to not only create energy, but also to heal itself.

So you have less damage.

Now, how much research is there elucidating the causal role of NAD in all this?

Because, I mean, it's one thing to decline in a way that's

associated with aging right but is the decline in nad have we determined whether or not the decline in nad is causally related to the dysfunction that we see related to aging that's a very good question and specifically relating to those orphan diseases we don't know if the non-detectable levels of nad is because that caused the disease or if it's just correlational because

the cells trying to cure some sort of DNA damage and consumes all the NAD in an effort to do that.

We don't know the answer to that question, if it's causal or correlational.

But we do know that by elevating NAD levels, the cell performs better.

That sounds auspicious.