Roxanne Khamsi
speaker
252 appearances
2 recordings
2 series
first heard Apr 2026
last heard 9 Jun
Roxanne Khamsi’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 2 in all, peaking in Jun 2026 with 1.
Appearances
So back in the late 1990s, for example, scientists found that there were these two boys in the New York area that were born with a type of immunodeficiency disorder.
that they were supposed to live in a bubble essentially their whole life.
And what they found, though, is that these two boys were defying any expectations.
Their immune systems were doing much better than the scientists expected.
And when they looked closely, they found that there actually had been mutations that these boys had acquired that had corrected their inherited disorder.
And it's not the only example.
So there's a disease called Fanconi anemia.
And about 20% of people with that disorder actually start having blood cells that correct the disease that they have.
And in 5% of those cases, they have enough that they start to progress towards just curing themselves.
So it is like finding the answer within.
So as you and I are talking, as people are listening, our DNA is just picking up mutations and some of these mutations will stick around for a while.
And the idea is that by the time we're older, we've kind of just amassed a bunch of mutation.
Now, the idea is, what happens if we might be able to undo some of the mutation that we acquire?
And I know that on this show, you guys have talked about bowhead whales and how they have a vast amount of DNA repair enzyme.
And this might be part of the reason they can live 200 years and longer.
So the question is, can we maybe replicate some of the DNA repair in those long-lived organisms to improve our longevity as well?
It is, yes, super tantalizing to think about this as a new avenue to anti-aging treatments.
But as you're pointing to, there's a lot of hype in this industry that happens.
And we want to make sure that we don't go too far in one direction without kind of having a reality check.
I think the important thing to recognize...
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