Sam Fazeli

speaker
906 appearances 5 recordings 1 series first heard Oct 2025 last heard 31 Mar

Sam Fazeli’s voice in public audio — every appearance, attributed to the second.

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recordings per month · last 12 months
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Recordings per month over the last 12 months — 5 in all, peaking in Mar 2026 with 2.

Appearances

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So I come up with my own pronunciation for stuff.
For sure.
Well, and they've been becoming very good at it, even better recently, making it major tongue twisters.
So let's touch on very quickly on HLX43.
We saw some data at WCLC for this agent, which is an antibody drug conjugate targeting PD-L1.
I am slightly biased towards drugs that use PD-L1 for a targeting agent.
methodology which of course from it you get kind of a double whammy you get potentially tumor targeting but of course PD-L1 is not just tumor cell expressed and you also get inhibition of PD-L1
So you get a double whammy in there, whereas if you just use a PD-1, in fact, you clearly risk killing the T-cells.
Talk to us a little bit about this agent and what your hopes are.
Here you're in a slightly different setup, recurrent metastatic esophageal carcinoma, squamous carcinoma, and actually advanced non-small cell lung cancer.
So talk to us a little bit about where this is going and where your hopes are.
Well, we're certainly watching it.
And, you know, as you talk about luck, I don't think any scientist would put luck aside ever as a major factor in their own success, in the success of their science.
And even companies, you know, I've just finished reading a completely unrelated autobiography of Bill Gates.
And when we are together for dinner, I could talk to you about the one event that I think happened, which was luck that enabled.
I mean, it's my view.
So anyway, just before we move on to the broader topic of China, is there you obviously have done NewCo with ForBeyond recently announced in August.
I do want to talk to us a little bit about that, and then we move on to China.
What is it?
Should we expect more?
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