Sam Rodriques

speaker

345 appearances 1 recordings 1 series first heard Dec 2025 last heard 26 Dec

Sam Rodriques’s voice in public audio — every appearance, attributed to the second.

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Recordings per month over the last 12 months — 1 in all, peaking in Dec 2025 with 1.

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Hard Fork · Where Is All the A.I.-Driven Scientific Progress? · 26 Dec 2025 podcast

It was able to identify what protein binds and what gene is being expressed and connected that to the actual mechanism of that gene, SSR1, which is involved in the pancreas in secreting insulin.

Right?

Yeah, that's right.

Okay.

And I think science generally consists of deciding what data to gather, gathering that data, and then drawing conclusions.

And so at this point, basically, it's like step number three that Cosmos is aimed at,

Yeah, absolutely.

You have to go and validate it.

And so that's actually one of the things also, you know, in the paper, actually, we describe how we went and validated that particular variant.

In general, when people are using it, yeah, you go in.

I mean, actually, literally, when you run a Cosmos run, the first thing you have to do is you have to understand what it's telling you, because it has just done something that scientists think is like six months worth of work.

And you're going to sit there for a long time, just like reading and understanding it.

Once you've read it and understood it, then yes, indeed, you're going to go and you're going to run various experiments, do your own analysis, cross-reference to try to convince yourself that this is true.

And then based on what your research objective is, you'll decide next steps, right?

You know, in this case,

I think it's probably low likelihood there's a new drug target from this particular finding, right?

But you could go and you could run this on other findings, and then eventually maybe you find a new drug target, you start a drug program, that's, you know.

So absolutely.

I actually like, you know, I really agree that like the bottleneck at the end of the day in solving medicine is basically, you know, clinical trials.

I mean, and the easiest way to see this is if you look at the number of diseases that we like know how to cure in mice.

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