Sydney Lupkin
speaker
1,064 appearances
108 recordings
3 series
first heard Dec 2024
last heard 4d ago
Sydney Lupkin’s voice in public audio — every appearance, attributed to the second.
Trend
recordings per month · last 12 monthsRecordings per month over the last 12 months — 93 in all, peaking in Jul 2026 with 21.
Appearances
And GLP-1, by the way, is a hormone your body naturally makes.
It stands for glucagon-like peptide 1.
It lasts much longer.
When Novo Nordisk made its medication version of GLP-1, the company tweaked it.
The active ingredient in both blockbuster drugs, Ozempic and Magovi, is called semaglutide.
Andrea explained how they made it.
Right.
By the way, there are four different blockbuster injectables.
Ozempic and Banjaro are for type 2 diabetes, and Wegovi and Zepbound are for obesity.
But the latest twist is that now there's a possibility of a pill.
Two pills, actually.
And to be clear, we're not talking about Rebelsis, which is a semaglutide pill, but it's approved for type 2 diabetes.
Got it.
Let's talk about the pill made by Novo Nordisk, whose active ingredient is semaglutide.
It's a peptide, a protein.
The problem is that in your stomach, the drug gets broken down too efficiently and too fast for the semaglutide to get into the bloodstream and do its job all over your body.
Andrea says to think about how your stomach breaks down some chicken that you've eaten.
Yeah, they added something to it.
I'll let Andrea explain it, but the gist is that this snack thing creates a little protective buffer zone around the pill to keep it from getting broken down too quickly and help it get absorbed into the bloodstream.
Then it can do all those other things to make you feel full and regulate blood sugar.
Showing 681–700 of 1,064 · page 35 of 54
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