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Vinay Prasad

👤 Person
142 total appearances

Appearances Over Time

Podcast Appearances

Talk Evidence
Talk Evidence covid-19 update - lack of testing transparency, how to give good debate

Because remember, there's a lot of activity we do, particularly in primary care, that actually is low value.

Talk Evidence
Talk Evidence covid-19 update - lack of testing transparency, how to give good debate

And I think this is an opportunity to separate out these two issues right now.

Talk Evidence
Talk Evidence covid-19 update - lack of testing transparency, how to give good debate

And I'm going to hark back because listeners to this programme will remember I talked about health screening earlier.

Talk Evidence
Talk Evidence covid-19 update - lack of testing transparency, how to give good debate

There's no evidence that reduces admissions or mortality in largely well people.

Talk Evidence
Talk Evidence covid-19 update - lack of testing transparency, how to give good debate

This is the time to get our act together and separate out these two issues.

Talk Evidence
Talk Evidence covid-19 update - lack of testing transparency, how to give good debate

You've got to keep saying it again and again and then it'll get through.

Talk Evidence
Talk Evidence covid-19 update - lack of testing transparency, how to give good debate

But this is the time to take the evidence.

Talk Evidence
Talk Evidence covid-19 update - lack of testing transparency, how to give good debate

Interestingly, it's worth noting in conditions like influenza, risk of deep vein thrombosis goes up.

Talk Evidence
Talk Evidence covid-19 update - lack of testing transparency, how to give good debate

In fact, with all of the respiratory infections, you're more at risk of a stroke, you're more at risk of a DVT.

Talk Evidence
Talk Evidence covid-19 update - lack of testing transparency, how to give good debate

So the first thing is to say, actually, you're likely to be more at risk with COVID of thrombosis.

Talk Evidence
Talk Evidence covid-19 update - lack of testing transparency, how to give good debate

with other conditions.

Talk Evidence
Talk Evidence covid-19 update - lack of testing transparency, how to give good debate

So once you understand that, the question is, are you more likely and is that one of the severe causes, the serious causes of death that actually could prevent?

Talk Evidence
Talk Evidence covid-19 update - lack of testing transparency, how to give good debate

That's a really interesting question.

Talk Evidence
Talk Evidence covid-19 update - lack of testing transparency, how to give good debate

This is one of the important trials that I would be looking at in hospitalised severe patients.

Talk Evidence
Talk Evidence covid-19 update - lack of testing transparency, how to give good debate

And interestingly, with a colleague of mine, Tom Jefferson, we posted a systematic review that had been withdrawn 20 years ago on treatments for the common cold, which, as everybody will know, one of the causes of the common cold is coronavirus.

Talk Evidence
Talk Evidence covid-19 update - lack of testing transparency, how to give good debate

And actually, going back 30 or 40 years ago, one of the interesting treatments people were looking at was dipyridamol.

Talk Evidence
Talk Evidence covid-19 update - lack of testing transparency, how to give good debate

And that actually has an effect.

Talk Evidence
Talk Evidence covid-19 update - lack of testing transparency, how to give good debate

It has an effect on platelets and we use it in people with stroke.

Talk Evidence
Talk Evidence covid-19 update - lack of testing transparency, how to give good debate

So I think there's a real mechanism argument for looking at treatments that actually may affect your circulatory system and actually putting them in trials.

Talk Evidence
Talk Evidence covid-19 update - lack of testing transparency, how to give good debate

Oh, okay.