Yasmeen Khan

One woman said her mood was dulled, and she couldn't enjoy her gardening hobby anymore.

And Kular told us we're still limited right now by the infancy of these studies and what happens when people stop taking the medications.

And of course, the drugs don't solve the root causes of addiction in the first place.

But Kular said that after writing his story, he was left feeling optimistic that these drugs could become an option for treatment.

And finally, a few other stories we're following.

Record snowfall hit the northeast and mid-Atlantic as a winter storm left two people dead in Maryland, hundreds of thousands without power in multiple states, and travel in the region significantly disrupted.

At least two feet of snow fell over four states and reported wind gusts reached hurricane levels in some areas.

Toppled power lines and trees were the main cause of outages.

Nearly 6,000 flights were canceled as a result of the storm.

In Rhode Island, a record 32.9 inches of snow fell, and in New York, close to 20 inches blanketed Central Park.

Authorities in Boston, which was heavily hit, said it could take up to the weekend to clear out the snow.

Officials in many areas are also warning people to stay off of roads because of dangerous conditions, and the National Weather Service says road travel is nearly impossible in the hardest-hit areas.

Violence continues in Mexico as cartel members retaliate against the killing of the country's top drug lord.

20 of Mexico's 32 states experienced violence as cars were torched in the resort city of Puerto Vallarta, and at least 25 Mexican soldiers were killed.

Flights from Mexico were suspended over safety concerns, leaving foreign travelers stranded.

Nemesio El Mencho Aceguera was killed in a military raid Sunday.

Authorities are bracing for bloody infighting among Aceguera's top lieutenants who were vying to take control of the syndicate, which had become the most powerful in Mexico.

The Wall Street Journal reports another civil war in the Sinaloa cartel could spill out into a wider territorial conflict as factions fight over drug routes.

And tonight, President Trump will deliver the first State of the Union address of his second term.

The speech comes a little over a year after Trump was inaugurated.