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Risk factors and risk-indicating model for early-onset neonatal sepsis after preterm prelabor rupture of membranes: A historical cohort study

03 Sep 2025

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Maternal diabetes, fever, positive urinary or vaginal/cervical culture, fetal tachycardia, and decreasing short-term variation were associated with an increased risk for EONS in a PPROM population. A model combining these risk factors performed better at indicating EONS risk than the clinicians' suspicion of intra-amniotic infection.Brynhildur Tinna Birgisdottir, Tomas Andersson, Ingela Hulthén Varli, Sissel Saltvedt, Farhad Abtahi, Ulrika Åden, Malin HolzmannFirst published: 01 June 2025 https://doi.org/10.1111/aogs.15168https://obgyn.onlinelibrary.wiley.com/toc/16000412/0/0

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