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Armchair Expert with Dax Shepard

Rachel Zoffness (on pain)

15 Apr 2026

Transcription

Transcript generated automatically by AI and may contain errors.

Chapter 1: What is discussed at the start of this section?

0.031 - 12.353 Dax Shepard

Welcome, welcome, welcome to Armchair Expert, Experts on Expert. I'm Dan Shepard. I'm joined by Lily Padman. Hi. We have a guest today with the cutest last name perhaps we've ever had, Rachel Zoffness.

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12.552 - 14.095 Unknown

Yeah, this was a great episode.

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14.495 - 15.417 Dax Shepard

I just love that last name.

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15.437 - 21.567 Unknown

It's a good last name. It's a little misleading because this isn't a Zoff episode.

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21.868 - 24.071 Dax Shepard

Although it is in also another way.

24.111 - 24.853 Unknown

I guess.

25.333 - 45.446 Dax Shepard

She is a leading pain psychologist and neuroscientist. You guys, this episode is so incredible. I think it's one of the best of the year. It's so many of us know, as you learn in here, There's 1.8 billion people in the world suffering from chronic pain. And there's 100 million Americans. And we don't understand how we experience pain, truly.

46.088 - 52.518 Dax Shepard

And this is an incredible explanation of how it actually works. And it's quite an empowering take on it.

52.538 - 53.039 Unknown

It is.

Chapter 2: Why is pain considered an empowering topic?

90.9 - 101.012 Dax Shepard

Are you a hugger? Yes, let's do it. Monica, you must know how this started. This is terrifying for me. I'm like a library mouse bookworm. I'm like not a public facing person.

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101.052 - 103.695 Unknown

Okay, well you're already so warm feeling.

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103.715 - 121.784 Dax Shepard

But listen to what happened. I saw Rob by the staircase when I left the house. So by the time I got out and went up the stairs to grab my drink, I saw that he was in the bathroom. And I go, Jesus, what are you taking a shit in there? It was Rachel. I was like, don't you wish I was?

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121.804 - 129.436 Unknown

Oh, no. Is that terrible? It's funny. Oh, my God. Did you get really scared?

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129.456 - 132.762 Dax Shepard

No. Good Lord. I know where I am. Come on.

Chapter 3: What is the significance of the biopsychosocial model in pain management?

134.124 - 134.765 Dax Shepard

Even for me.

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Yeah, even for you.

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135.907 - 154.936 Dax Shepard

You would not do that. We have a friend in common also. Who? Do you see the person who wrote the endorsement on the top of the book? Who did it? Oh, I did see that. Yes. Anna Lemke. I'm obsessed with her. Oh, yes. She's the reason I teach at Stanford. Because addiction, medicine, and pain are best friends. Yeah, that's right. So you're down presumably from San Francisco. Do you live there?

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154.956 - 173.984 Dax Shepard

Yeah, I'm in the Bay Area. But I'm originally a New Yorker, which is why I have an attitude problem and I wear too much black and I curse all the time. I feel like I'm in good company. Those are good attributes. I thought you said you were like a church mouse. Library mouse? Very, very different than church mouse. Yeah, super different. People are pervs. I think.

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174.004 - 195.678 Dax Shepard

They're like in the nurse category. What's happening? Don't know what's happening. Yeah, no. I was like the kid who was shy and quiet. Shy and quiet. Quiet and shy. And was in the library reading all the time. Books for my friends. Different than a church mouse. That is different. You're right. How has teaching been for you? Because that requires a ton of get up in front of people and speak.

195.939 - 213.176 Dax Shepard

What's funny is that during the pandemic, this thing happened where I was supposed to give all these talks and I was actually doing that because it was partially a treatment for my own performance anxiety and public speaking anxiety. The treatment is exposure therapy, right? Like if you never do it, you never get through it. So I had all these talks planned and then everything got canceled.

213.837 - 231.473 Dax Shepard

I was like, okay, what do I do now? So I started planning virtual talks and I started cold pitching podcast hosts. And I pitched a couple of people who actually had really big platforms and I didn't realize it at the time. As I started doing more and more podcasts, I think I did like 42 of them. Wow. Oh my goodness. And like Ezra Klein came calling.

231.694 - 244.275 Dax Shepard

And by the time I did that one, I had done so many that I felt pretty secure in what I wanted to say. And I feel very passionate about the topic. And I keep my patience in my mind when I talk about the topic. So I'm sweating through my clothes.

244.375 - 247.42 Unknown

Well, that's also because it's 500 degrees. I'm so hot.

Chapter 4: How do psychological factors influence the experience of pain?

551.401 - 569.35 Dax Shepard

I love telling people that, like, when you take a drug, the drug itself isn't the thing that's giving you the sensation. That's right. It's either regulating uptake or down. It's just letting the chemicals in your body go crazy. And it's binding to receptors that your brain has because your brain already makes those chemicals. Yeah. Exactly. Which is why you adjust.

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It's in you. It's not whatever you're putting in.

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571.373 - 589.44 Dax Shepard

So like if you're taking a drug for a very long period of time, your brain does a thing where it down-regulates. You probably have heard this term from the other science nerds you've had on where your brain stops producing as much of that thing. So if you're taking chronic opioids, for example, your brain doesn't need to produce as many because you're giving them from an external source.

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589.58 - 603.111 Dax Shepard

So you down-regulate. You don't have as many. Now... neurotransmitters in your brain and the receptors are just picking up what you're giving it instead of like the homemade ones. Take me to San Diego State. Oh, right. Take me there. We're still on the education journey. This is hard for me, by the way. I hate talking about myself.

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603.131 - 621.602 Dax Shepard

I guess what I'm trying to figure out when I asked about your parents and you, I guess there's two versions of this. One is... I have anxiety. I'm afraid to pick. I don't really know what my calling is. I'm scared. Another one is I'm at this salad bar and I just can't stop going up to it and trying something new. It was the latter. Yeah.

621.722 - 640.186 Dax Shepard

And also I really wanted to make sure I was going in the right direction because it's a lot of time when you go to school for that long. Like you really want to be sure as shit that this is the right direction. So I just kept honing it and honing it. So San Diego State UCSD was where I went for my PhD. And I studied clinical psychology because I decided I wanted to work with patients.

640.547 - 662.439 Dax Shepard

And I really was fascinated by the brain-body overlap. I still feel this way. I felt like if I had gone to med school, I would have gotten like one slice of the pie. And if I went for my PhD in psychology, I would get another. And I wanted the intersection. And I had to kind of go get that on my own, to be perfectly honest. Yeah, we just had Michael Pollan on last week. I just saw him at a diner.

662.459 - 670.833 Dax Shepard

He lives in my neighborhood. I almost went up to him and I was like, that's rude. I'm not going to do that. Oh, he probably would have liked it. That must be so annoying. Oh, I don't think so.

670.853 - 673.478 Unknown

It's only annoying if you go and tell him about your shroom trip.

Chapter 5: How does social medicine relate to emotional health?

4053.422 - 4062.612 Unknown

I need these people. Social medicine is real. Yes. Obviously, if I exercise, I feel better. I'm not as regimented as that. That's okay.

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4062.632 - 4063.513 Dax Shepard

I'm also 12 years older.

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If I'm in a good routine, I use exercise all the time. So if I'm in a good routine, yes.

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Chapter 6: What is the significance of therapy in managing pain?

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But I think the social medicine is a huge one.

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4070.981 - 4075.566 Dax Shepard

I want to add, I don't want to pat myself on the back. You do what you have to do.

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Yeah.

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4076.654 - 4096.714 Dax Shepard

You're humming along. Again, you're 12 years younger than me. I do what I have to do to not be miserable. If I got to do less and not be miserable, I would do it. I had to go to AA because I was going to die. I didn't go because I wanted to go. Like, I also think you can look at someone else's routine and feel some kind of shame that you're not executing all this stuff.

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4096.754 - 4100.257 Dax Shepard

But you should only be doing what you have to do. This is what I have to do.

4100.317 - 4104.643 Unknown

That's true. Like, there are moments where I'm like, I... have to go on a walk.

Chapter 7: What are the challenges of addressing addiction in treatment?

4104.663 - 4110.252 Unknown

My body and brain know that I just maybe need to do it on the same frequency or I don't know, whatever.

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4110.432 - 4130.229 Dax Shepard

But yeah, mainly that. Fanatical schedule. Well, no, I didn't say that. I found your low pain recipe and I think it's really amazing. And you guys listed all the things that I would put like taking care of emotional health other than when I think of emotional health support, I actually think it's great to talk to someone. And there's so much stigma around that still. It's like 20, 20,000.

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4130.53 - 4136.384 Dax Shepard

And here we are and we're still talking about like, it's so shameful to have to see a therapist. So like, I want to see if I can frame this differently.

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4136.785 - 4141.377 Unknown

Sorry, I can't believe I didn't say that. I can't believe I didn't start with that. I'm in therapy. Yeah, yeah.

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4141.618 - 4164.48 Dax Shepard

And it's... It's hard to find someone who's available at the times you want, who's qualified, who you like and trust and want to talk to. So I'm not saying it's easy, but research shows it can be extremely, extremely helpful. Just as we go to the gym all the time to exercise our bodies and make our bodies stronger, why would we not engage in some form of brain exercise for our emotional health?

4164.46 - 4166.163 Dax Shepard

When I think of therapy, that's what I think of.

Chapter 8: How do societal perceptions affect pain management?

4166.243 - 4185.855 Dax Shepard

We're going to a trained professional who's helping us with our emotional health, with our history of trauma, with our fucked up relationships with our families. Doesn't everybody need that just as much as we need to go on a jog? How much better a place would the world be if we were all engaging in as much brain exercise as body exercise? So I think about that also.

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4186.135 - 4207.134 Dax Shepard

Yeah, I think my reservation there a little bit is I am always... conscious, I think, because of where it came from, with how lofty a lot of these are. If you have two jobs and you have two kids and you're a single parent, A, I don't have the money for therapy. And I don't have the free time to exercise, like you're saying. These are all real, real pressures.

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4207.575 - 4229.909 Dax Shepard

But even to that, I would argue like AA is free. There's a lot of different groups that are free. You can actually engage in group therapy in a lot of ways for free. I would also argue that to prioritize 20 minutes of movement in the day. You could go for five. You'd really be shocked how much time that buys you the rest of it because you're no longer in that destructive cycle.

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4229.929 - 4246.973 Dax Shepard

You're in the virtuous cycle. So you might be shocked with how taking more time for that thing ends up adding time. I think it's a fair and a good point. And the affordability piece is a really huge one. And I think there are a lot of resources out there. There are even workbooks that can help with certain things like depression and anxiety. That's why I like your book.

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4247.073 - 4260.575 Dax Shepard

Someone can get your book and go through this. The purpose of writing the book was sort of like to put the power into hands of anybody who wants to understand it and treat it. You have techniques for modifying negative thoughts. True story. That's great. Social medicine, we just talked about that.

4260.775 - 4281.865 Dax Shepard

Some things that could help that will weirdly downriver affect pain is like better boundaries, creating healthy social connections, healing trauma. These things all impact your experience with pain. Yep. My other curiosity was, again, I brought up AA. AA has abysmal success numbers. Is that true? Oh, yeah. It's in the, like, 30%. But... I did not know.

4281.885 - 4303.108 Dax Shepard

Relative to the other treatments, it's an absolute miracle. You can look at it one of two ways. If you want to just go, like, only 30-some percent of people who go there end up getting long-term sobriety, sure. But versus the alternative is, like, single digit. People don't just quit. I mean, very few people just... white knuckle it for the rest of their lives.

4303.309 - 4325.374 Dax Shepard

So I'm curious, we know how abysmal the outcome of chronic pain treatment is with doctors. It's in the low, you know, it's under 50%. What kind of success would you say you were experiencing with this more holistic? Oh, this is going to make me sound like a jerk. Okay. Like a brat. Here's why I'm sitting here on your couch despite performance and public speaking anxiety. Yeah.

4325.394 - 4347.896 Dax Shepard

My patients get better. They get out of bed and they go back to life. I am not saying that their pain disappears completely all of the time. That would make me a liar. Sam continued to have pain flares. but he knew what to do. They didn't paralyze him and they didn't keep him bedridden. He knew what to do. If he needed to rest, he would rest. But he wasn't on the white food diet.

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