In this episode of Cutaneous Miscellaneous, host Nicholas Brownstone, MD, welcomes Naiem Issa, MD, for an in-depth discussion on topical therapies in dermatology, covering both traditional treatments and the latest innovations, focusing on tapinarof and roflumilast. The episode begins with a board review of eczematous and papulosquamous diseases, including CARP, asteatotic eczema, nummular dermatitis, and pityriasis rosea, highlighting key diagnostic clues, treatment approaches, and must-know information for residents. They then explore the role of topical therapies in treating psoriasis and atopic dermatitis, emphasizing patient expectations, positioning treatments effectively, and the balance between topicals and systemic options. They provide insights into newer agents like tapinarof and roflumilast, discussing their mechanisms of action, clinical use, and combination strategies for enhanced efficacy. The episode wraps up with practical pearls for residents, including how to navigate access issues, gain hands-on experience with new therapies, and stay updated on emerging therapies. Tune in for a high-yield discussion packed with clinical takeaways!

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