Royal Wounds: King George III, Stress Biology, and Diabetic Foot Healing

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Recorded04 Jan 2026

Publisherfeed.podbean.com ↗

Handlerec:15097275

Show notes

This episode examines King George III's documented episodes of severe mental illness and modern re-evaluation (bipolar disorder vs porphyria), then connects the biology of stress—HPA axis, cortisol, and catecholamines—to impaired diabetic foot ulcer healing. It explains how depression, agitation, and self-neglect worsen outcomes and outlines a humane, multidisciplinary modern treatment plan that pairs wound care with psychiatric and geriatric support to improve limb salvage.

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