BONUS: Preserving Muscle During Weight Loss with Angelo Keely | Menopause, Perimenopause, Muscle Health

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Recorded24 Aug 2026

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I’m excited to share another episode in our series of highly vetted companies. Today, I’m delighted to reconnect with Angelo Keely, the Co-founder and CEO of Kion, for our third conversation. I’ve been using essential aminos. I really leaned into them during my book launch, and I credit them with helping me maintain my muscle mass despite training at a lower volume. In today’s conversation, Angelo and I discuss GLP-1s and muscle loss, exploring protein intake, the leucine threshold hypothesis, the association between declining estrogen and blunted muscle protein synthesis, and using essential aminos to build and maintain muscle. We unpack the role of sleep and recovery for muscle health, daily versus as-needed creatine monohydrate and essential amino acid supplementation, what omega-3s are, why they matter, and how to supplement. We also cover midlife women's body composition, weight loss, and muscle building, and Angelo shares his take on the disconnect between body composition changes in midlife women and how companies actively market to midlife women, knowing the challenges we face in that area. Stay tuned for today’s insightful and informative discussion with Angelo Keely of Kion. IN THIS EPISODE, YOU WILL LEARN: How caloric restriction leads to fat loss but can also cause the body to break down muscle How essential aminos can help preserve our muscles as we age The essential amino formula Angelo recommends for midlife women Hormone changes may affect muscle protein synthesis The huge impact poor sleep has on whole-body protein synthesis Essential aminos vs. whey protein and how they differ Value of essential aminos for maintaining muscle during caloric deficits How aminos and creatine both need to be taken consistently, but for different physiological reasons What to look for when choosing a quality omega-3 supplement How to make daily supplementation easier to maintain Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia’s website. Submit your questions to [email protected] Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow. Purchase Cynthia’s book, The Menopause Gut. Cynthia’s Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Connect with Angelo Keely Kion (Use code CYNTHIA for 20% off)

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