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Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

Ep. 521 Metabolism Masterclass: Weight Loss Resistance Explained with Cynthia Thurlow, NP

19 Nov 2025

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Today, we have the first episode in a two-part mashup series focused on metabolism and weight loss resistance.  I am delighted to be joined today by Dr. William Li, Michelle Shapiro, and Lara Adler. Dr. Li and I explore how our metabolism shifts throughout our lifetime, the role of excess body fat, the influence of lifestyle choices, and the distinction between different types of fat. Michelle and I discuss the complex relationship between weight, shame, and self-perception, including how internal dialogue, orthorexia, and adverse childhood events shape our health journey. Lara and I examine how metabolic health and insulin resistance are affected by the endocrine-disrupting chemicals found in everyday products, food, and the environment.  You will love this invaluable compilation, packed with insights and practical knowledge from our expert guests. IN THIS EPISODE, YOU WILL LEARN: How metabolism changes as we age The difference between brown (biologically active) and white fat  Excess body fat drives inflammation and hormonal changes. How our internal dialogue influences our lifestyle choices  Impact of adverse childhood experiences on long-term health and stress responses Dietary strategies can fail when driven by fear or perfectionism. Endocrine-disrupting chemicals block or mimic hormones  Early-life chemical exposures set the stage for lifelong metabolic challenges Reducing toxic exposure can support weight management and metabolic resilience.  How reducing your exposure to endocrine-disrupting chemicals present in everyday products can support your metabolic health and help you manage your weight  Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to [email protected] Connect with Dr. William Li On social media: @Dr William Li On his website Sign up for Dr. Li’s free newsletter  Ep. 354 Metabolism Myths Debunked: Weight Gain Insights with Dr. William Li Connect with Michelle Shapiro On her website Quiet the Diet Podcast Ep. 390 Understanding Shame, Food Behaviors & Weight Loss with Michelle Shapiro Connect with Lara Adler On her website On Facebook and Instagram Ep. 159 Lara Adler Explains The Link Between Chemical Exposure And Weight Gain & Other Health Issues

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