Ep. 611 "What the Pill & Depo Do to Your Bones" | Menopause, Perimenopause, Bone Health

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Recorded25 Jun 2026

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Welcome to the latest Midlife Minute. Today, we’re discussing how oral contraceptives and Depo Provera can impact women’s bone health over time.Stay tuned as I walk you through the research, prescribing trends, and ways women can support their bone health. IN THIS EPISODE, YOU WILL LEARN: How peak bone mass in adolescence affects bone health later in life How oral contraceptives can interfere with the bone development of young women The lack of informed conversations about the bone health risks associated with long-term contraceptive use Why Depo Provera may have a stronger impact on bone density than oral contraceptives The importance of nutrition and strength training for supporting bone health How hormonal contraceptives can affect the gut microbiome and immune system What you need to consider regarding your bone density and long-term health if you’ve been using oral contraceptives or Depo for many years Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia’s website. Submit your questions to [email protected] Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow. Purchase Cynthia’s book, The Menopause Gut. Cynthia’s Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Resources: Depot medroxyprogesterone acetate, oral contraceptives and bone mineral density in a cohort of adolescent girls doi:10.1016/j.jadohealth.2004.07.005 Oral Contraceptive Use and Bone Density Change in Adolescent and Young Adult Women: A Prospective Study of Age, Hormone Dose, and Discontinuation doi:10.1210/jc.2010-3027 Adolescent use of combined hormonal contraception and peak bone mineral density accrual: A meta-analysis of international prospective controlled studies doi:10.1111/cen.13932 No need to specialize: reproductive health is for all adolescents doi:10.1016/j.jpag.2006.01.055 Injectable Hormone Contraception and Bone Density: Results from a Prospective Study doi:10.1097/00001648-200209000-00015 Hormonal contraception and the development of autoimmunity: A review of the literature doi:10.1080/00243639.2017.1360065 Oral contraceptives, reproductive factors and risk of inflammatory bowel disease doi:10.1136/gutjnl-2012-302362 Combined oral contraceptive use and the risk of systemic lupus erythematosus doi:10.1002/art.24398 Oral Contraceptives and Multiple Sclerosis/Clinically Isolated Syndrome Susceptibility doi:10.1371/journal.pone.0149094 The Experience of Surviving a High-Risk Pregnancy doi:10.1080/23293691.2016.1166104 Effects of 0.9 mg Recombinant Human Thyrotropin on Thyroid Size and Function in Normal Subjects: A Randomized, Double-Blind, Cross-Over Trial doi:10.1210/jc.2004-0914

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