An Alzheimer's blood test is on the way. What could that mean for you?

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Health Report 43 min 7 speakers 5 chapters transcribed 1 month ago
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Tegan Taylor 0:00
ABC Listen. Podcasts, radio, news, music and more. Hey, Tegan Taylor here from Life Matters. Do you rely on grandparents to help pay the bills or look after the kids? You're not alone. Life has gotten busier, more expensive and grandparents are picking up the slack. This July on Radio National, The Grandparent Trap explores the changing role of grandparents in modern family life. The Grandparent Trap and much more on Life Matters. Search for Life Matters on ABC Listen or wherever you get your podcasts.
Priya Alexander 0:38
So Priya, if I was to offer you a test for Alzheimer's disease, would you take it? Oh, I'd have a lot of questions. In the bloom of youth?
Norman Swan 0:47
Well, it depends because I have no symptoms. So is it a diagnostic test or a screening test? And if it's a screening test, I would have to think very hard.
Priya Alexander 0:56
A lot of news this week about the Alzheimer's blood test and we're going to explore just what that means.
Norman Swan 1:02
And that's what's coming up on this week's health report.
Priya Alexander 1:05
I'm Norman Swan on Gadigal land.
Norman Swan 1:07
And I'm Priya Alexander on Wurundjeri land.
Priya Alexander 1:12
Also on the show today, the remarkable story behind this new Ebola vaccine. In fact, there's four new Ebola vaccines in development and how they're operating at high speed.
Norman Swan 1:22
And in terms of medical abortion rates, Australia is very low compared to high-income countries. Why is that the case? In general practice, there is a study that's looked at access and why maybe our rates are so low. Very interesting.
Norman Swan 1:42
In the news, endometriosis is something we've covered a lot of on the Health Report recently, and women still wait up to seven years for a diagnosis, so there can still be a long period with no diagnosis, pelvic pain, heavy vaginal bleeding, lots of symptoms. There may be a saliva test that is available to women in Australia soon, and health reporter Lauren Roberts from the Northern Territory has done a digital piece on this. Lauren, thank you for joining us on the Health Report. Thank you for having me. So what is the test? It's a saliva test.
Lauren Roberts 2:13
What is it looking for? It's a probability test. So I'll just be clear with that straight up front. It's called the Z-Wig EndoTest. It's from a French startup. And what it does is it looks for tiny non-coding RNA molecules and it's looking for patterns which have been linked with endometriosis. And then it kind of analyzes all of that with the help of artificial intelligence and

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Lauren Roberts 2:36
and return some data which indicates whether someone likely has endometriosis based on these patterns or likely doesn't.
Priya Alexander 2:44
And presumably because it's a probability test, there's all of leeway as to whether or not it's accurate.
Lauren Roberts 2:48
Well, yes. And this is why we kind of need the real world data. So there's a couple of studies going on at the moment. One is in France. That's an 18 month study. We should have results of that later this year. And there's a three year trial that's happening in the United Kingdom at the moment. So both of those are going to give us a bit of a better understanding about how this test works in the real world, because it's kind of just been tested in small specific settings at the moment. And the manufacturer says that it can pick up 97% of people with endometriosis and 93% percent of people that don't have the disease
Norman Swan 3:21
And it's not meant to replace transvaginal ultrasound or laparoscopy where they go in and actually have a look for the tissue. It's kind of an adjuvant, is it? It's an add-on in the workup.
Lauren Roberts 3:32
Yeah, well, they're using it as a complementary diagnostic tool in the United Kingdom at the moment, which is how they're kind of seeing how it fits in with the existing system. So at the moment, what they're doing is trying to cut down the long wait times that a lot of people do experience on a specialist recommendation using the endotest. And then based on the results from that, they can make different recommendations. Because even a transvaginal ultrasound, it can be quite uncomfortable or painful for someone with endometriosis if they have tight vaginal muscles. So even though that in Australia is the best recommendation for the first line treatment, it's not always smooth.

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